Prebiotics, gut microbiota and metabolic risks: Unveiling the relationship

Adeela Yasmin*, Masood Sadiq Butt, Muhammad Afzaal, Marleen van Baak, Muhammad Tahir Nadeem, Muhammad Zia Shahid

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Web of Science)


The human gastrointestinal tract is colonized by trillions of microbes comprising thousands of bacterial phylotypes. Recent metagenomic studies of the human gut microbiota have revealed the presence of millions of genes, as compared to genes present in the entire human body. Perturbation in the level of gut microorganisms may lead to the onset of metabolic disorders. However, compelling evidence has also suggested that a particular gut microbial community may halt the occurrence of metabolic risk factors. Restoration of the beneficial gut microbial balance is difficult to achieve but the exploitation of prebiotics has led to promising outcomes in various studies.
Original languageEnglish
Pages (from-to)189-201
JournalJournal of Functional Foods
Publication statusPublished - Aug 2015


  • Metabolic disorders
  • Prebiotics
  • Gut microbes
  • Bifidobacteria
  • Hypercholesterolaemia
  • Hyperglycaemia

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