Pre-hospitale Beta-blockers in ST-elevation acute myocardial infarction = Pre-hospitale beta-blocker toediening in acuut myocard infarct.

Vincent Roolvink

Research output: ThesisDoctoral ThesisExternal prepared

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The extent of myocardial infarction is an important determinant of mortality. Beta-blockers are a type of medication often prescribed after myocardial infarction. These drugs slow down the heart rate. However, little is known about the effect of beta-blockers on the extent of myocardial infarction, if administrated in an ambulance, i.e. prior to percutaneous angioplasty. This dissertation shows that early administration of beta-blockers does not reduce the extent of infarction, nor mortality. It does prevent arrhythmia during the acute phase after myocardial infarction and has only few side effects. Patients who have already been receiving long-term beta-blocker therapy are not at increased risk of cardiogenic shock when suffering myocardial infarction.
Original languageEnglish
Awarding Institution
  • Maastricht University
  • van 't Hof, Arnoud, Supervisor
  • Ottervanger, Jan Paul, Co-Supervisor, External person
Award date29 Jun 2018
Place of PublicationMaastricht
Print ISBNs9789463611039
Publication statusPublished - 2018


  • myocardial infarction
  • mortality
  • beta-blockers
  • cardiogenic shock

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