Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life

Lisa S van Tol*, Miriam L Haaksma, Matteo Cesari, Frances Dockery, Irma H J Everink, Bahaa N Francis, Adam L Gordon, Stefan Grund, Luba Matchekhina, Laura Monica Perez Bazan, Jos M G A Schols, Eva Topinková, Mark A Vassallo, Monique A A Caljouw, Wilco P Achterberg, EU-COGER consortium

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: After an acute infection, older persons may benefit from geriatric rehabilitation (GR). Objectives: This study describes the recovery trajectories of post-COVID-19 patients undergoing GR and explores whether frailty is associated with recovery. Design: Multicentre prospective cohort study. Setting: 59 GR facilities in 10 European countries. Participants: Post-COVID-19 patients admitted to GR between October 2020 and October 2021. Methods: Patients’ characteristics, daily functioning (Barthel index; BI), quality of life (QoL; EQ-5D-5L) and frailty (Clinical Frailty Scale; CFS) were collected at admission, discharge, 6 weeks and 6 months after discharge. We used linear mixed models to examine the trajectories of daily functioning and QoL. Results: 723 participants were included with a mean age of 75 (SD: 9.91) years. Most participants were pre-frail to frail (median [interquartile range] CFS 6.0 [5.0–7.0]) at admission. After admission, the BI first steeply increased from 11.31 with 2.51 (SE 0.15, P < 0.001) points per month and stabilised around 17.0 (quadratic slope: −0.26, SE 0.02, P < 0.001). Similarly, EQ-5D-5L first steeply increased from 0.569 with 0.126 points per month (SE 0.008, P < 0.001) and stabilised around 0.8 (quadratic slope: −0.014, SE 0.001, P < 0.001). Functional recovery rates were independent of frailty level at admission. QoL was lower at admission for frailer participants, but increased faster, stabilising at almost equal QoL values for frail, pre-frail and fit patients. Conclusions: Post-COVID-19 patients admitted to GR showed substantial recovery in daily functioning and QoL. Frailty at GR admission was not associated with recovery and should not be a reason to exclude patients from GR.

Original languageEnglish
Article numberafae084
Number of pages10
JournalAge and Ageing
Volume53
Issue number5
DOIs
Publication statusPublished - 1 May 2024

Keywords

  • COVID-19
  • geriatric rehabilitation
  • older people
  • recovery
  • Humans
  • COVID-19/rehabilitation epidemiology psychology
  • Quality of Life
  • Aged
  • Female
  • Male
  • Activities of Daily Living
  • Prospective Studies
  • Aged, 80 and over
  • Geriatric Assessment/methods
  • Frailty/diagnosis rehabilitation psychology
  • Frail Elderly
  • Recovery of Function
  • SARS-CoV-2
  • Europe

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