Poly(caprolactone-co-trimethylenecarbonate) urethane acrylate resins for digital light processing of bioresorbable tissue engineering implants

Tobias Kuhnt; Ramiro Marroquin Garcia; Sandra Camarero Espinosa; Clemens van Blitterswijk; Lorenzo Moroni; Matt Baker

doi:10.1039/C9BM01042D

Poly(caprolactone-co-trimethylenecarbonate) urethane acrylate resins for digital light processing of bioresorbable tissue engineering implants

Tobias Kuhnt
, Ramiro Marroquin Garcia
, Sandra Camarero Espinosa
, Clemens van Blitterswijk
, Lorenzo Moroni^*
, Matt Baker^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To exploit the usability of Digital Light Processing (DLP) in regenerative medicine, biodegradable, mechanically customizable and
well-defined polyester urethane acrylate resins were synthesized
based on poly(caprolactone-co-trimethlenecarbonate). By controlling the monomer ratio, the resultant fabricated constructs
showed tunable mechanical properties, degradation and attached
hMSC morphologies.

Original language	English
Pages (from-to)	4984-4989
Number of pages	6
Journal	Biomaterials Science
Volume	7
Issue number	12
DOIs	https://doi.org/10.1039/C9BM01042D
Publication status	Published - 1 Dec 2019

Keywords

biomaterials
tissue engineering
POLYMERS
EPSILON-CAPROLACTONE
BEHAVIOR
STEREOLITHOGRAPHY
TRIMETHYLENE CARBONATE
POLY(PROPYLENE FUMARATE)
DEGRADATION
POLYMERIZATION
SCAFFOLDS
RING-OPENING COPOLYMERIZATION

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@article{a500f7e3bc82407c8277f603f7cf4bda,

title = "Poly(caprolactone-co-trimethylenecarbonate) urethane acrylate resins for digital light processing of bioresorbable tissue engineering implants",

abstract = "To exploit the usability of Digital Light Processing (DLP) in regenerative medicine, biodegradable, mechanically customizable and well-defined polyester urethane acrylate resins were synthesized based on poly(caprolactone-co-trimethlenecarbonate). By controlling the monomer ratio, the resultant fabricated constructs showed tunable mechanical properties, degradation and attached hMSC morphologies.",

keywords = "biomaterials, tissue engineering, POLYMERS, EPSILON-CAPROLACTONE, BEHAVIOR, STEREOLITHOGRAPHY, TRIMETHYLENE CARBONATE, POLY(PROPYLENE FUMARATE), DEGRADATION, POLYMERIZATION, SCAFFOLDS, RING-OPENING COPOLYMERIZATION",

author = "Tobias Kuhnt and \{Marroquin Garcia\}, Ramiro and \{Camarero Espinosa\}, Sandra and \{van Blitterswijk\}, Clemens and Lorenzo Moroni and Matt Baker",

note = "Funding Information: This work was supported financially by the Province of Limburg and the Brightlands Materials Center. Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",

year = "2019",

month = dec,

day = "1",

doi = "10.1039/C9BM01042D",

language = "English",

volume = "7",

pages = "4984--4989",

journal = "Biomaterials Science",

issn = "2047-4830",

publisher = "Royal Society of Chemistry",

number = "12",

}

TY - JOUR

T1 - Poly(caprolactone-co-trimethylenecarbonate) urethane acrylate resins for digital light processing of bioresorbable tissue engineering implants

AU - Kuhnt, Tobias

AU - Marroquin Garcia, Ramiro

AU - Camarero Espinosa, Sandra

AU - van Blitterswijk, Clemens

AU - Moroni, Lorenzo

AU - Baker, Matt

PY - 2019/12/1

Y1 - 2019/12/1

N2 - To exploit the usability of Digital Light Processing (DLP) in regenerative medicine, biodegradable, mechanically customizable and well-defined polyester urethane acrylate resins were synthesized based on poly(caprolactone-co-trimethlenecarbonate). By controlling the monomer ratio, the resultant fabricated constructs showed tunable mechanical properties, degradation and attached hMSC morphologies.

AB - To exploit the usability of Digital Light Processing (DLP) in regenerative medicine, biodegradable, mechanically customizable and well-defined polyester urethane acrylate resins were synthesized based on poly(caprolactone-co-trimethlenecarbonate). By controlling the monomer ratio, the resultant fabricated constructs showed tunable mechanical properties, degradation and attached hMSC morphologies.

KW - biomaterials

KW - tissue engineering

KW - POLYMERS

KW - EPSILON-CAPROLACTONE

KW - BEHAVIOR

KW - STEREOLITHOGRAPHY

KW - TRIMETHYLENE CARBONATE

KW - POLY(PROPYLENE FUMARATE)

KW - DEGRADATION

KW - POLYMERIZATION

KW - SCAFFOLDS

KW - RING-OPENING COPOLYMERIZATION

U2 - 10.1039/C9BM01042D

DO - 10.1039/C9BM01042D

M3 - Article

SN - 2047-4830

VL - 7

SP - 4984

EP - 4989

JO - Biomaterials Science

JF - Biomaterials Science

IS - 12

ER -

Poly(caprolactone-co-trimethylenecarbonate) urethane acrylate resins for digital light processing of bioresorbable tissue engineering implants

Abstract

Keywords

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