Pneumatosis cystoides intestinalis, four cases of a rare disease

R.J.W.M Rennenberg*, G.H. Koek, P. van Hootegem, R.W. Stockbrügger

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Pneumatosis cystoides intestinalis (PCI) is a disease in which small gas-filled cysts appear in the intestinal wall. Four cases presented here demonstrate the diversity of the associated diseases. In two of the patients constipation probably played a role; in the third patient decreased colonic motility, elevated intestinal pressure and increased mucosal permeability in the context of enteritis treated with codeine was the underlying problem; in the fourth high protein feeding and bowel ischaemia was diagnosed. Various aetiologies are presented in the literature. There is no specific history and physical or laboratory findings do not help to diagnose PCI. Plain abdominal film, ultrasound, computer tomography, magnetic resonance imaging, barium contrast studies and/or endoscopy may be necessary for diagnosis. Therapy is based on enhancing partial oxygen pressure in the bowel wall. PCI usually runs a benign course.
Original languageEnglish
Pages (from-to)22-25
Number of pages4
JournalNetherlands Journal of Medicine
Issue number1
Publication statusPublished - 1 Jan 2002

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