Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels

Sandra den Hoedt, Carola I. F. Janssen, Giuseppe Astarita, Daniele Piomelli, Frank P. J. Leijten, Simone M. Crivelli, Adrie J. M. Verhoeven, Helga E. de Vries, Jochen Walter, Pilar Martinez-Martinez, Eric J. G. Sijbrands, Amanda J. Kiliaan, Monique T. Mulder*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)769-781
Number of pages13
JournalJournal of Alzheimer's Disease
Volume60
Issue number3
DOIs
Publication statusPublished - 3 Oct 2017

Keywords

  • Alzheimer's disease
  • apolipoprotein E4
  • ceramides
  • fatty acids
  • high fat diet
  • sphingolipids
  • MOUSE APOLIPOPROTEIN-E
  • HIGH-CHOLESTEROL DIET
  • AMYLOID-BETA PEPTIDE
  • BLOOD-BRAIN-BARRIER
  • KNOCK-IN MICE
  • ALZHEIMERS-DISEASE
  • BINDING PROTEIN
  • SPHINGOLIPID METABOLISM
  • NEURODEGENERATIVE DISEASES
  • DENSITY-LIPOPROTEIN

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