Platelets, from sample to big data: exploring granularity in platelet research

This dissertation focuses on platelet function. The function of platelets in the coagulation process was studied in depth by using advanced measurement instruments in laboratory and clinical settings in which platelets were strongly stimulated (such as cold, pressure, artificial heart, surgical oncology). We also studied how platelet information included in major information streams, as seen in patients admitted to an intensive care unit, can be processed. By using this type of information technology, care can be better tailored to the needs of the individual patient, taking into account the patient’s unique medical history, and genetic and metabolic footprint.