Platelet Counts in the First Seven Days of Life and Patent Ductus Arteriosus in Preterm Very Low-Birth-Weight Infants

Maria Pilar Bas-Suarez, Gema Esther Gonzalez-Luis, Pedro Saavedra, Eduardo Villamor*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Background: Decreased platelet number and/or function are related to patent ductus arteriosus (PDA) in mice. Whether this is also the case in human infants remains controversial. Objectives: To investigate the association between platelet count nadir within the first 7 days of life and the rate of hemodynamically significant PDA (HSPDA), as well as the rate of response to the treatment with cyclooxygenase (COX) inhibitors. Methods: This is a retrospective study of a cohort of 194 very low-birth-weight (VLBW) infants (
Original languageEnglish
Pages (from-to)188-194
JournalNeonatology
Volume106
Issue number3
DOIs
Publication statusPublished - 2014

Keywords

  • Ductus arteriosus
  • Platelet
  • Thrombocytopenia
  • Very low birth weight

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