Plasma Levels of Dimethylarginines in Preterm Very Low Birth Weight Neonates: Its Relation with Perinatal Factors and Short-Term Outcome

Rob M. Moonen, Maurice J. Huizing, Giacomo Cavallaro, Gema E. Gonzalez-Luis, Pilar Bas-Suarez, Jaap A. Bakker, Eduardo Villamor*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Web of Science)

Abstract

Endogenously produced inhibitors of nitric oxide (NO) synthase, in particular asymmetric dimethylarginine (ADMA), are currently considered of importance in various disease states characterized by reduced NO availability. We investigated the association between plasma levels of ADMA, symmetric dimethylarginine (SDMA), L-arginine, and citrulline and perinatal factors and outcome in 130 preterm (gestational age
Original languageEnglish
Pages (from-to)19-39
JournalInternational Journal of Molecular Sciences
Volume16
Issue number1
DOIs
Publication statusPublished - Jan 2015

Keywords

  • dimethylarginine
  • arginine
  • preterm infants
  • nitric oxide
  • preeclampsia
  • chrorioamnionitis
  • respiratory distress

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