Plaque vulnerability in stroke patients: a multimodality imaging approach

Research output: ThesisDoctoral ThesisInternal


In the Netherlands, 126 people suffer from a stroke every day. One of the causes of stroke is atherosclerosis, or plaque build-up, in the carotid arteries. Depending on the severity of the condition, the plaque can be surgically removed to prevent a recurrent stroke.

This study aimed to contribute to improved patient selection for surgical interventions by examining the composition of the plaque using imaging techniques such as MRI, CT and PET-CT scans. The study found that these images could be reliably interpreted by different assessors and that the composition of the plaque did not change over the course of a year. Further research is needed to determine which technique has the highest predictive value for determining a recurrent ischemic stroke.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • Mess, Werner, Supervisor
  • Wildberger, Joachim, Supervisor
  • Kooi, M.E., Co-Supervisor, External person
Award date19 Feb 2016
Publication statusPublished - 2016


  • ischemic stroke
  • atherosclerosis
  • MRI
  • CT
  • PET-CT

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