@inproceedings{e13cbe5e0b30473998527d774b91a02f,
title = "Physiological versus non-physiological cardiac pacing as assessed by Ultra-high-frequency electrocardiography",
abstract = "Background: Permanent cardiac pacing can cause heart failure, with the ventricular dyssynchrony being identified as the main cause for its development.Method: His bundle pacing (HBp), left bundle branch pacing (LBBp), and left ventricular myocardial septal pacing (LVSP) were introduced recently. Their impact on ventricular dyssynchrony was not known. We used ultra-high-frequency ECG (UHF-ECG) to compare ventricular depolarization in these pacing techniques.Results: We showed the nonselective HB pacing produces the same pattern of UHF-ECG ventricular depolarization as selective HB pacing. Next, we showed the nonselective His bundle pacing in the area below the tricuspid valve has the best interventricular synchrony from all other RV pacing locations with myocardial capture. We also compared UHF-ECG-derived parameters of ventricular depolarization during HBp, LBBp, and LVSP and we showed that both pacing types from the left septal area are less physiological than nsHBp.Conclusion: UHF-ECG is an effective tool that can be used in clinical practice to assess the electrical dyssynchrony caused by cardiac pacing. Furthermore, its real-time implementation allows recognizing between physiological vs. non-physiological pacing during an implant procedure.",
keywords = "DYSSYNCHRONY, PREDICTORS, BUNDLE",
author = "K. Curila and P. Jurak and P. Leinveber and R. Smisek and P. Stros and F. Plesinger and I. Viscor and V. Vondra and J. Mizner and O. Sussenbek and L. Znojilova and J. Karch and M. Susankova and J. Halamek and F.W. Prinzen",
note = "Funding Information: Work was supported by the Charles University Research Program Q38, Research Centre program No. UNCE/MED/002, 260530/SVV/2020, Ministry of Health of the Czech Republic, grant number NU21-02-00584, and the Czech Academy of Sciences (project RVO:68081731). Publisher Copyright: {\textcopyright} 2021 Creative Commons.; Conference on Computing in Cardiology (CinC) ; Conference date: 12-09-2021 Through 15-09-2021",
year = "2021",
doi = "10.23919/CinC53138.2021.9662912",
language = "English",
series = "Computing in Cardiology Conference",
publisher = "IEEE",
booktitle = "2021 COMPUTING IN CARDIOLOGY (CINC)",
address = "United States",
}