Physical Activity, Occupational Sitting Time, and Colorectal Cancer Risk in the Netherlands Cohort Study

Colinda C. J. M. Simons; Laura A. E. Hughes; Manon van Engeland; R. Alexandra Goldbohm; Piet A. van den Brandt; Matty P. Weijenberg

doi:10.1093/aje/kws280

Physical Activity, Occupational Sitting Time, and Colorectal Cancer Risk in the Netherlands Cohort Study

Colinda C. J. M. Simons^*, Laura A. E. Hughes, Manon van Engeland, R. Alexandra Goldbohm, Piet A. van den Brandt, Matty P. Weijenberg

^*Corresponding author for this work

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Abstract

We investigated occupational energy expenditure and sitting time in the longest held job (in men only), nonoccupational physical activity, and former sports participation in relation to colorectal cancer endpoints. The Netherlands Cohort Study includes 120,852 participants who completed a self-administered questionnaire in 1986 when they were aged 55-69 years. By 2002, 1,819 male and 1,366 female colorectal cancer cases were available for case-cohort analyses. In men, higher occupational energy expenditure levels and fewer occupational sitting hours were associated with decreased hazard ratios for colon cancer, particularly distal colon cancer (occupational energy expenditure of >= 12 vs. 90 vs. 90 vs.

Original language	English
Pages (from-to)	514-530
Journal	American Journal of Epidemiology
Volume	177
Issue number	6
DOIs	https://doi.org/10.1093/aje/kws280
Publication status	Published - 15 Mar 2013

Keywords

cohort studies
colonic neoplasms
physical activity
rectal neoplasms
sedentary lifestyle

Access to Document

10.1093/aje/kws280

Full TextFinal published version, 174 KBLicence: Taverne

Cite this

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title = "Physical Activity, Occupational Sitting Time, and Colorectal Cancer Risk in the Netherlands Cohort Study",

abstract = "We investigated occupational energy expenditure and sitting time in the longest held job (in men only), nonoccupational physical activity, and former sports participation in relation to colorectal cancer endpoints. The Netherlands Cohort Study includes 120,852 participants who completed a self-administered questionnaire in 1986 when they were aged 55-69 years. By 2002, 1,819 male and 1,366 female colorectal cancer cases were available for case-cohort analyses. In men, higher occupational energy expenditure levels and fewer occupational sitting hours were associated with decreased hazard ratios for colon cancer, particularly distal colon cancer (occupational energy expenditure of >= 12 vs. 90 vs. 90 vs. ",

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AU - Goldbohm, R. Alexandra

AU - van den Brandt, Piet A.

AU - Weijenberg, Matty P.

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KW - colonic neoplasms

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