TY - JOUR
T1 - Physical Activity in End-Stage Renal Disease Patients
T2 - The Effects of Starting Dialysis in the First 6 Months after the Transition Period
AU - Broers, Natascha J. H.
AU - Martens, Remy J. H.
AU - Cornelis, Tom
AU - van der Sande, Frank M.
AU - Diederen, Nanda M. P.
AU - Hermans, Marc M. H.
AU - Wirtz, Joris J. J. M.
AU - Stifft, Frank
AU - Konings, Constantijn J. A. M.
AU - Dejagere, Tom
AU - Canaud, Bernard
AU - Wabel, Peter
AU - Leunissen, Karel M. L.
AU - Kooman, Jeroen P.
PY - 2017
Y1 - 2017
N2 - Objectives: Physical inactivity in end-stage renal disease (ESRD) patients is associated with increased mortality, and might be related to abnormalities in body composition (BC) and physical performance. It is uncertain to what extent starting dialysis influences the effects of ESRD on physical activity (PA). This study aimed to compare PA and physical performance between stage 5 chronic kidney disease (CKD-5) non-dialysis and dialysis patients, and healthy controls, to assess alterations in PA during the transition from CKD-5 non-dialysis to dialysis, and to relate PA to BC. Methods: For the cross-sectional analyses 44 CKD-5 non-dialysis patients, 29 dialysis patients, and 20 healthy controls were included. PA was measured by the SenseWear (TM) pro3. Also, the walking speed and handgrip strength (HGS) were measured. BC was measured by the Body Composition Monitor (c). Longitudinally, these parameters were assessed in 42 CKD-5 nondialysis patients (who were also part of the cross-sectional analysis), before the start of dialysis and 6 months thereafter. Results: PA was significantly lower in CKD-5 non-dialysis patients as compared to that in healthy controls but not as compared to that in dialysis patients. HGS was significantly lower in dialysis patients as compared to that in healthy controls. Walking speed was significantly lower in CKD-5 non-dialysis patients as compared to that in healthy controls but not as compared to that in dialysis patients. Six months after starting dialysis, activity related energy expenditure (AEE) and walking speed significantly increased. Conclusions: PA is already lower in CKD-5 non-dialysis patients as compared to that in healthy controls and does not differ from that of dialysis patients. However, the transition phase from CKD-5 non-dialysis to dialysis is associated only with a modest improvement in AEE. (C) 2017 The Author(s) Published by S. Karger AG, Basel
AB - Objectives: Physical inactivity in end-stage renal disease (ESRD) patients is associated with increased mortality, and might be related to abnormalities in body composition (BC) and physical performance. It is uncertain to what extent starting dialysis influences the effects of ESRD on physical activity (PA). This study aimed to compare PA and physical performance between stage 5 chronic kidney disease (CKD-5) non-dialysis and dialysis patients, and healthy controls, to assess alterations in PA during the transition from CKD-5 non-dialysis to dialysis, and to relate PA to BC. Methods: For the cross-sectional analyses 44 CKD-5 non-dialysis patients, 29 dialysis patients, and 20 healthy controls were included. PA was measured by the SenseWear (TM) pro3. Also, the walking speed and handgrip strength (HGS) were measured. BC was measured by the Body Composition Monitor (c). Longitudinally, these parameters were assessed in 42 CKD-5 nondialysis patients (who were also part of the cross-sectional analysis), before the start of dialysis and 6 months thereafter. Results: PA was significantly lower in CKD-5 non-dialysis patients as compared to that in healthy controls but not as compared to that in dialysis patients. HGS was significantly lower in dialysis patients as compared to that in healthy controls. Walking speed was significantly lower in CKD-5 non-dialysis patients as compared to that in healthy controls but not as compared to that in dialysis patients. Six months after starting dialysis, activity related energy expenditure (AEE) and walking speed significantly increased. Conclusions: PA is already lower in CKD-5 non-dialysis patients as compared to that in healthy controls and does not differ from that of dialysis patients. However, the transition phase from CKD-5 non-dialysis to dialysis is associated only with a modest improvement in AEE. (C) 2017 The Author(s) Published by S. Karger AG, Basel
KW - Body composition
KW - Dialysis
KW - End-stage renal disease
KW - Physical activity
KW - CHRONIC KIDNEY-DISEASE
KW - AMBULATORY PERITONEAL-DIALYSIS
KW - LOWER-EXTREMITY FUNCTION
KW - HEMODIALYSIS-PATIENTS
KW - BODY-COMPOSITION
KW - MUSCLE STRENGTH
KW - SUBSEQUENT DISABILITY
KW - INTERNATIONAL COHORT
KW - SENSEWEAR ARMBAND
KW - OLDER ADULTS
U2 - 10.1159/000476072
DO - 10.1159/000476072
M3 - Article
C2 - 28591752
VL - 137
SP - 47
EP - 56
JO - The Nephron Journals
JF - The Nephron Journals
SN - 1660-8151
IS - 1
ER -