TY - JOUR
T1 - Physical activity and weight loss are independent predictors of improved insulin sensitivity following energy restriction
AU - Camps, Stefan G. J. A.
AU - Verhoef, Sanne P. M.
AU - Westerterp, Klaas R.
PY - 2016/2
Y1 - 2016/2
N2 - Objective The role of physical activity and the joint effect with sleep duration on insulin sensitivity (IS) during energy restriction followed by weight maintenance were determined. MethodsOne hundred and two subjects (28 males) (meanSD age: 409years; BMI: 31.9 +/- 3.0kg/m(2)) followed a very-low-energy diet for 8weeks, followed by a 44-week period of weight maintenance. Body composition (three-compartment model based on body weight, total body water, and body volume), physical activity (accelerometry), sleep (questionnaire, Epworth Sleepiness Scale), and fasting plasma insulin and glucose concentrations were assessed before the diet and at 8, 20, and 52weeks after the start. ResultsCompared to baseline, IS was improved significantly after 8weeks (P
AB - Objective The role of physical activity and the joint effect with sleep duration on insulin sensitivity (IS) during energy restriction followed by weight maintenance were determined. MethodsOne hundred and two subjects (28 males) (meanSD age: 409years; BMI: 31.9 +/- 3.0kg/m(2)) followed a very-low-energy diet for 8weeks, followed by a 44-week period of weight maintenance. Body composition (three-compartment model based on body weight, total body water, and body volume), physical activity (accelerometry), sleep (questionnaire, Epworth Sleepiness Scale), and fasting plasma insulin and glucose concentrations were assessed before the diet and at 8, 20, and 52weeks after the start. ResultsCompared to baseline, IS was improved significantly after 8weeks (P
U2 - 10.1002/oby.21325
DO - 10.1002/oby.21325
M3 - Article
C2 - 26813523
SN - 1930-7381
VL - 24
SP - 291
EP - 296
JO - Obesity
JF - Obesity
IS - 2
ER -