Phosphodiesterase Inhibitors in Object Recognition and Object Location Memory Tests

Pim R.A. Heckman*, Elentina K. Argyrousi*, Jos Prickaerts*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

Phosphodiesterase (PDE) inhibitors prevent hydrolyzation of the second messengers cyclic adenosine monophosphate and cyclic guanosine monophosphate; they are considered promising cognitive enhancers. Object recognition and object location tests contributed significantly to the advancement of current research on PDE inhibitors in memory, ageing and Alzheimer's disease research studies.
Original languageEnglish
Title of host publicationHandbook of Object Novelty Recognition
EditorsAbdel Ennaceur, Maria Angelica de Souza Silva
PublisherElsevier
Chapter38
Pages567-574
Number of pages8
Volume27
ISBN (Print)978-0-12-812012-5
DOIs
Publication statusPublished - 2018

Keywords

  • cAMP
  • cGMP
  • Neuroplasticity
  • Object recognition
  • Phosphodiesterase inhibitors

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