TY - JOUR
T1 - Phenotypic Characteristics of Patients With Chronic Obstructive Pulmonary Disease After Stratification for the Short Physical Performance Battery Summary Score
AU - Stoffels, Anouk A. F.
AU - De Brandt, Jana
AU - Meys, Roy
AU - van Hees, Hieronymus W. H.
AU - Vaes, Anouk W.
AU - Klijn, Peter
AU - Burtin, Chris
AU - Franssen, Frits M. E.
AU - van den Borst, Bram
AU - Sillen, Maurice J. H.
AU - Wouters, Emiel F. M.
AU - Janssen, Daisy J. A.
AU - Spruit, Martijn A.
AU - BASES Consortium
PY - 2020/11
Y1 - 2020/11
N2 - Objective: To assess the phenotypic characteristics of patients with chronic obstructive pulmonary disease (COPD) after stratification for Short Physical Performance Battery (SPPB) summary scores and to determine phenotypic characteristics of the SPPB summary score at the start of pulmonary rehabilitation (PR).Design: Retrospective, cross-sectional.Setting: Baseline assessment for PR program.Participants: Patients with COPD (n=900; age 65 +/- 8y, 52% male, forced expiratory volume in the first second of expiration, 43% [interquartile range, 31%-62%] predicted).Interventions: Not applicable.Main Outcome Measures: Patients were stratified according to their SPPB summary scores into low-performance (LP), moderate-performance (MP), or high-performance (HP) groups. Furthermore, lung function, arterial blood gases, body composition, physical capacity, lower limb muscle strength and endurance, and symptoms of anxiety and depression were assessed.Results: Generally, physical capacity and muscle function were lower and scores for symptoms of anxiety and depression were higher in LP patients than MP and HP patients (all values, P= 10 points), and HP patients still had on average an impaired physical capacity (median, 6-minute walk test [6MWT] distance of 69% predicted). Furthermore, age and 6MWT distance (m) were the only independent predictors in a multivariate regression model, explaining 29% of the variance in SPPB summary score.Conclusions: In COPD, LP patients have the worst physical and emotional functioning. However, HP patients can still exhibit physical and emotional impairments. Because the explained variance in SPPB summary score is low, SPPB should not be considered as a test to discriminate between patients with COPD with a low or preserved physical capacity and emotional status. (C) 2020 by the American Congress of Rehabilitation Medicine
AB - Objective: To assess the phenotypic characteristics of patients with chronic obstructive pulmonary disease (COPD) after stratification for Short Physical Performance Battery (SPPB) summary scores and to determine phenotypic characteristics of the SPPB summary score at the start of pulmonary rehabilitation (PR).Design: Retrospective, cross-sectional.Setting: Baseline assessment for PR program.Participants: Patients with COPD (n=900; age 65 +/- 8y, 52% male, forced expiratory volume in the first second of expiration, 43% [interquartile range, 31%-62%] predicted).Interventions: Not applicable.Main Outcome Measures: Patients were stratified according to their SPPB summary scores into low-performance (LP), moderate-performance (MP), or high-performance (HP) groups. Furthermore, lung function, arterial blood gases, body composition, physical capacity, lower limb muscle strength and endurance, and symptoms of anxiety and depression were assessed.Results: Generally, physical capacity and muscle function were lower and scores for symptoms of anxiety and depression were higher in LP patients than MP and HP patients (all values, P= 10 points), and HP patients still had on average an impaired physical capacity (median, 6-minute walk test [6MWT] distance of 69% predicted). Furthermore, age and 6MWT distance (m) were the only independent predictors in a multivariate regression model, explaining 29% of the variance in SPPB summary score.Conclusions: In COPD, LP patients have the worst physical and emotional functioning. However, HP patients can still exhibit physical and emotional impairments. Because the explained variance in SPPB summary score is low, SPPB should not be considered as a test to discriminate between patients with COPD with a low or preserved physical capacity and emotional status. (C) 2020 by the American Congress of Rehabilitation Medicine
KW - Anxiety
KW - Depression
KW - Physical fitness
KW - Physical functional
KW - performance
KW - Postural balance
KW - Pulmonary disease
KW - chronic obstructive
KW - Pulmonary Rehabilitation
KW - LOWER-EXTREMITY FUNCTION
KW - FAT-FREE MASS
KW - ELDERLY-PEOPLE
KW - DISABILITY
KW - SARCOPENIA
KW - VALIDITY
KW - DISTANCE
KW - DECLINE
KW - RISK
KW - COPD
U2 - 10.1016/j.apmr.2020.05.011
DO - 10.1016/j.apmr.2020.05.011
M3 - Article
C2 - 32497598
VL - 101
SP - 1887
EP - 1897
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
SN - 0003-9993
IS - 11
ER -