Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months

Suzanne Leijen; Robin M. J. M. van Geel; Gabe S. Sonke; Daphne de Jong; Efraim H. Rosenberg; Serena Marchetti; Dick Pluim; Erik van Werkhoven; Shelonitda Rose; Mark A. Lee; Tomoko Freshwater; Jos H. Beijnen; Jan H. M. Schellens

doi:10.1200/JCO.2016.67.5942

Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months

Suzanne Leijen, Robin M. J. M. van Geel, Gabe S. Sonke, Daphne de Jong, Efraim H. Rosenberg, Serena Marchetti, Dick Pluim, Erik van Werkhoven, Shelonitda Rose, Mark A. Lee, Tomoko Freshwater, Jos H. Beijnen, Jan H. M. Schellens

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	4354-4363
Journal	Journal of Clinical Oncology
Volume	34
Issue number	36
DOIs	https://doi.org/10.1200/JCO.2016.67.5942
Publication status	Published - 20 Dec 2016

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10.1200/JCO.2016.67.5942

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Leijen, S., van Geel, R. M. J. M., Sonke, G. S., de Jong, D., Rosenberg, E. H., Marchetti, S., Pluim, D., van Werkhoven, E., Rose, S., Lee, M. A., Freshwater, T., Beijnen, J. H., & Schellens, J. H. M. (2016). Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months. Journal of Clinical Oncology, 34(36), 4354-4363. https://doi.org/10.1200/JCO.2016.67.5942

Leijen, Suzanne ; van Geel, Robin M. J. M. ; Sonke, Gabe S. ; de Jong, Daphne ; Rosenberg, Efraim H. ; Marchetti, Serena ; Pluim, Dick ; van Werkhoven, Erik ; Rose, Shelonitda ; Lee, Mark A. ; Freshwater, Tomoko ; Beijnen, Jos H. ; Schellens, Jan H. M. / Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months. In: Journal of Clinical Oncology. 2016 ; Vol. 34, No. 36. pp. 4354-4363.

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title = "Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months",

author = "Suzanne Leijen and {van Geel}, {Robin M. J. M.} and Sonke, {Gabe S.} and {de Jong}, Daphne and Rosenberg, {Efraim H.} and Serena Marchetti and Dick Pluim and {van Werkhoven}, Erik and Shelonitda Rose and Lee, {Mark A.} and Tomoko Freshwater and Beijnen, {Jos H.} and Schellens, {Jan H. M.}",

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doi = "10.1200/JCO.2016.67.5942",

language = "English",

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Leijen, S, van Geel, RMJM, Sonke, GS, de Jong, D, Rosenberg, EH, Marchetti, S, Pluim, D, van Werkhoven, E, Rose, S, Lee, MA, Freshwater, T, Beijnen, JH & Schellens, JHM 2016, 'Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months', Journal of Clinical Oncology, vol. 34, no. 36, pp. 4354-4363. https://doi.org/10.1200/JCO.2016.67.5942

Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months. / Leijen, Suzanne; van Geel, Robin M. J. M.; Sonke, Gabe S.; de Jong, Daphne; Rosenberg, Efraim H.; Marchetti, Serena; Pluim, Dick; van Werkhoven, Erik; Rose, Shelonitda; Lee, Mark A.; Freshwater, Tomoko; Beijnen, Jos H.; Schellens, Jan H. M.

In: Journal of Clinical Oncology, Vol. 34, No. 36, 20.12.2016, p. 4354-4363.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months

AU - Leijen, Suzanne

AU - van Geel, Robin M. J. M.

AU - Sonke, Gabe S.

AU - de Jong, Daphne

AU - Rosenberg, Efraim H.

AU - Marchetti, Serena

AU - Pluim, Dick

AU - van Werkhoven, Erik

AU - Rose, Shelonitda

AU - Lee, Mark A.

AU - Freshwater, Tomoko

AU - Beijnen, Jos H.

AU - Schellens, Jan H. M.

PY - 2016/12/20

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U2 - 10.1200/JCO.2016.67.5942

DO - 10.1200/JCO.2016.67.5942

M3 - Article

C2 - 27998224

VL - 34

SP - 4354

EP - 4363

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

SN - 0732-183X

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ER -