Pharmacological inhibition of 17 beta-hydroxysteroid dehydrogenase impairs human endometrial cancer growth in an orthotopic xenograft mouse model

Sofia Xanthoulea*, Gonda F. J. Konings, Niina Saarinen, Bert Delvoux, Loes F. S. Kooreman, Pasi Koskimies, Merja R. Hakkinen, Seppo Auriola, Elisabetta D'Avanzo, Youssef Walid, Frank Verhaegen, Natasja G. Lieuwes, Florian Caiment, Roy Kruitwagen, Andrea Romano, ENITEC

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)18-29
Number of pages12
JournalCancer Letters
Volume508
DOIs
Publication statusPublished - 28 Jun 2021

Keywords

  • 17 beta-estradiol
  • FP4643
  • 17 beta-HSD-1 inhibitor
  • Ishikawa
  • Bioluminescence imaging
  • COLORECTAL-CANCER
  • MESENCHYMAL TRANSITION
  • TYPE-1
  • CELL
  • IDENTIFICATION
  • INCREASES
  • INVASION
  • THERAPY
  • TARGET
  • MICE

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