Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

Erika M. Palmieri, Alessio Menga, Rosa Martin-Perez, Annamaria Quinto, Carla Riera-Domingo, Giacoma De Tullio, Douglas C. Hooper, Wouter H. Lamers, Bart Ghesquiere, Daniel W. McVicar, Attilio Guarini, Massimiliano Mazzone, Alessandra Castegna

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1654-1666
Number of pages13
JournalCell Reports
Volume20
Issue number7
DOIs
Publication statusPublished - 15 Aug 2017

Keywords

  • INNATE IMMUNITY
  • CELL MIGRATION
  • METABOLISM
  • POLARIZATION
  • EXPRESSION
  • INFLAMMATION
  • ACTIVATION
  • CANCER
  • DEFICIENCY
  • PLASTICITY

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