Permitting patients to pay for participation in clinical trials: the advent of the P4 trial

David Shaw; Guido de Wert; Wybo Dondorp; David Townend; Gerard Bos; Michel van Gelder

doi:10.1007/s11019-016-9741-2

Permitting patients to pay for participation in clinical trials: the advent of the P4 trial

David Shaw^*, Guido de Wert, Wybo Dondorp, David Townend, Gerard Bos, Michel van Gelder

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In this article we explore the ethical issues raised by permitting patients to pay for participation (P4) in clinical trials, and discuss whether there are any categorical objections to this practice. We address key considerations concerning payment for participation in trials, including patient autonomy, risk/benefit and justice, taking account of two previous critiques of the ethics of P4. We conclude that such trials could be ethical under certain strict conditions, but only if other potential sources of funding have first been explored or are unavailable.

Original language	English
Pages (from-to)	219-227
Number of pages	9
Journal	Medicine Health Care and Philosophy
Volume	20
Issue number	2
DOIs	https://doi.org/10.1007/s11019-016-9741-2
Publication status	Published - Jun 2017

Keywords

Clinical trials
Research ethics
Participatory research
Exploitation
Patient participation
Crowdfunding

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10.1007/s11019-016-9741-2Licence: CC BY

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abstract = "In this article we explore the ethical issues raised by permitting patients to pay for participation (P4) in clinical trials, and discuss whether there are any categorical objections to this practice. We address key considerations concerning payment for participation in trials, including patient autonomy, risk/benefit and justice, taking account of two previous critiques of the ethics of P4. We conclude that such trials could be ethical under certain strict conditions, but only if other potential sources of funding have first been explored or are unavailable.",

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author = "David Shaw and {de Wert}, Guido and Wybo Dondorp and David Townend and Gerard Bos and {van Gelder}, Michel",

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AU - Shaw, David

AU - de Wert, Guido

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AU - Townend, David

AU - Bos, Gerard

AU - van Gelder, Michel

PY - 2017/6

Y1 - 2017/6

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AB - In this article we explore the ethical issues raised by permitting patients to pay for participation (P4) in clinical trials, and discuss whether there are any categorical objections to this practice. We address key considerations concerning payment for participation in trials, including patient autonomy, risk/benefit and justice, taking account of two previous critiques of the ethics of P4. We conclude that such trials could be ethical under certain strict conditions, but only if other potential sources of funding have first been explored or are unavailable.

KW - Clinical trials

KW - Research ethics

KW - Participatory research

KW - Exploitation

KW - Patient participation

KW - Crowdfunding

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DO - 10.1007/s11019-016-9741-2

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JF - Medicine Health Care and Philosophy

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ER -

Permitting patients to pay for participation in clinical trials: the advent of the P4 trial

Abstract

Keywords

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