Background/Aims: Clinical outcome in cardiorenal syndrome type II and treated with peritoneal dialysis (PD). Methods: Retrospective analysis over a period of 10 years. Results: Twenty-four patients with mean age at start of dialysis of 67 +/- 10 years had mean survival on dialysis of 1.03 +/- 0.84 years (median survival 1.0 year). The number of hospitalizations for cardiovascular causes were reduced (13.7 +/- 26.5 predialysis vs. 3.5 +/- 8.8 days/patient/month postdialysis, p = 0.001). Patients who survived longer than the median survival time (n = 12) also had a reduced number of hospitalizations for all causes (3.7 +/- 3.8 predialysis vs. 1.4 +/- 2.1 days/patient/month postdialysis, p = 0.041), a lower age (62 +/- 10 vs. 71 +/- 8 years, p = 0.013) and fewer had diabetes (2 vs. 7 patients, p = 0.039), but left ventricular ejection fraction was not different. Conclusion: After starting PD for cardiorenal syndrome, hospitalizations for cardiovascular causes were reduced for all patients. Survival after starting PD is highly variable. Age and diabetes seem to be significant prognostic factors, but not left ventricular ejection fraction.