Percutaneous treatment of mechanical complications of acute myocardial infarction: state of the art

Daniele Ronco, Matteo Matteucci*, Giulio Massimi, Vittoria Lodo, Sara Garis, Arianna Scarantino, Corinne Messina, Alessandra Francica, Marco Russo, Roberto Lorusso, Fabio Barili, Alessandro Parolari, Nome SICCH Young Task Force

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Left ventricular free wall rupture, ventricular pseudoaneurysm, papillary muscle rupture and ventricular septal rupture are life-threatening mechanical complications of acute myocardial infarction. Despite significant improvements over the last decades in overall mortality for patients with myocardial infarction, the outcome of subjects who develop post-infarction mechanical complications remains poor. Surgical treatment is considered the standard of care. However, percutaneous approaches (such as pericardial fibrin-glue injection for left ventricular free wall rupture, transcatheter edge-to-edge mitral repair for papillary muscle rupture and device closure for ventricular pseudoaneurysm or septal rupture) have been proposed in selected high-risk or inoperable patients, or in subjects with ideal characteristics for feasibility, as therapeutic alternatives to open surgery. The aim of the present review is to provide a comprehensive overview of the percutaneous strategies for the management of post-acute myocardial infarction mechanical complications.
Original languageItalian
Pages (from-to)615-623
Number of pages9
JournalGiornale Italiano di Cardiologia
Volume25
Issue number9
Publication statusPublished - 1 Sept 2024

Keywords

  • Myocardial infarction
  • Papillary muscle rupture
  • Ventricular free wall rupture
  • Ventricular pseudoaneurysm
  • Ventricular septal rupture
  • VENTRICULAR SEPTAL-DEFECT
  • PAPILLARY-MUSCLE RUPTURE
  • FREE-WALL RUPTURE
  • TRANSCATHETER CLOSURE
  • CORONARY INTERVENTION
  • MITRAL REGURGITATION
  • OUTCOMES
  • REPAIR
  • INJECTION
  • OCCLUDER

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