PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease

Magdalena Krochmal*, Marco Fernandes, Szymon Filip, Claudia Pontillo, Holger Husi, Jerome Zoidakis, Harald Mischak, Antonia Vlahou, Joachim Jankowski*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Web of Science)

Abstract

The peptiCKDdb is a publicly available database platform dedicated to support research in the field of chronic kidney disease (CKD) through identification of novel biomarkers and molecular features of this complex pathology. PeptiCKDdb collects peptidomics and proteomics datasets manually extracted from published studies related to CKD. Datasets from peptidomics or proteomics, human case/control studies on CKD and kidney or urine profiling were included. Data from 114 publications (studies of body fluids and kidney tissue: 26 peptidomics and 76 proteomics manuscripts on human CKD, and 12 focusing on healthy proteome profiling) are currently deposited and the content is quarterly updated. Extracted datasets include information about the experimental setup, clinical study design, discovery-validation sample sizes and list of differentially expressed proteins (P-value
Original languageEnglish
Article numberbaw128
JournalDatabase-The Journal of Biological Databases and Curation
Volume2016
DOIs
Publication statusPublished - 1 Sep 2016

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