PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease

Magdalena Krochmal; Marco Fernandes; Szymon Filip; Claudia Pontillo; Holger Husi; Jerome Zoidakis; Harald Mischak; Antonia Vlahou; Joachim Jankowski

doi:10.1093/database/baw128

PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease

Magdalena Krochmal^*, Marco Fernandes, Szymon Filip, Claudia Pontillo, Holger Husi, Jerome Zoidakis, Harald Mischak, Antonia Vlahou, Joachim Jankowski^*

^*Corresponding author for this work

Pathologie

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Web of Science)

Abstract

The peptiCKDdb is a publicly available database platform dedicated to support research in the field of chronic kidney disease (CKD) through identification of novel biomarkers and molecular features of this complex pathology. PeptiCKDdb collects peptidomics and proteomics datasets manually extracted from published studies related to CKD. Datasets from peptidomics or proteomics, human case/control studies on CKD and kidney or urine profiling were included. Data from 114 publications (studies of body fluids and kidney tissue: 26 peptidomics and 76 proteomics manuscripts on human CKD, and 12 focusing on healthy proteome profiling) are currently deposited and the content is quarterly updated. Extracted datasets include information about the experimental setup, clinical study design, discovery-validation sample sizes and list of differentially expressed proteins (P-value

Original language	English
Article number	baw128
Journal	Database-The Journal of Biological Databases and Curation
Volume	2016
DOIs	https://doi.org/10.1093/database/baw128
Publication status	Published - 1 Sep 2016

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10.1093/database/baw128

Cite this

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title = "PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease",

abstract = "The peptiCKDdb is a publicly available database platform dedicated to support research in the field of chronic kidney disease (CKD) through identification of novel biomarkers and molecular features of this complex pathology. PeptiCKDdb collects peptidomics and proteomics datasets manually extracted from published studies related to CKD. Datasets from peptidomics or proteomics, human case/control studies on CKD and kidney or urine profiling were included. Data from 114 publications (studies of body fluids and kidney tissue: 26 peptidomics and 76 proteomics manuscripts on human CKD, and 12 focusing on healthy proteome profiling) are currently deposited and the content is quarterly updated. Extracted datasets include information about the experimental setup, clinical study design, discovery-validation sample sizes and list of differentially expressed proteins (P-value ",

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AU - Krochmal, Magdalena

AU - Fernandes, Marco

AU - Filip, Szymon

AU - Pontillo, Claudia

AU - Husi, Holger

AU - Zoidakis, Jerome

AU - Mischak, Harald

AU - Vlahou, Antonia

AU - Jankowski, Joachim

PY - 2016/9/1

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