Pediatric Pulmonary Hypertension in the Netherlands Epidemiology and Characterization During the Period 1991 to 2005

Rosa Laura E. van Loon, Marcus T. R. Roofthooft, Hans L. Hillege, Arend D. J. ten Harkel, Magdalena van Osch-Gevers, Tammo Delhaas, Livia Kapusta, Jan L. M. Strengers, Lukas A. J. Rammeloo, Sally-Ann B. Clur, Barbara J.M. Mulder, Rolf M. F. Berger*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

154 Citations (Web of Science)


Background-Incidence and prevalence rates for pediatric pulmonary hypertension (PH) and pulmonary arterial hypertension (PAH) are unknown. This study describes the nationwide epidemiological features of pediatric PH in the Netherlands during a 15-year period and the clinical course of pediatric PAH. Methods and Results-Two registries were used to retrospectively identify children (0-17 years) with PH. Overall, 3263 pediatric patients were identified with PH due to left heart disease (n = 160; 5%), lung disease/hypoxemia (n = 253; 8%), thromboembolic disease (n = 5;
Original languageEnglish
Pages (from-to)1755-U136
Issue number16
Publication statusPublished - 18 Oct 2011


  • pulmonary hypertension
  • pediatric
  • epidemiology
  • incidence
  • prevalence

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