Pediatric delirium in the pediatric intensive care unit: a systematic review and an update on key issues and research questions

C. Creten, S. Van Der Zwaan, Roos J. Blankespoor, P. L. J. M. Leroy, J. N. M. Schieveld*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Web of Science)


There was a dearth in awareness and knowledge regarding pediatric delirium (PD) at the pediatric intensive care unit (PICU). The aim of this study is to highlight the most recent and up-to-date findings of current literature -by means of a systematic review (SR) method-, and to present the key issues and research questions. A SR of the literature published between 24 March 2009 and 10 March 2011. Eight new articles were identified which included (literature) reviews, journal commentaries, and observational studies. There still is a dearth of literature on PD, with also a variable level of evidence (1b - 5), especially in relation to critical illness. To be able to further clarify PD in the PICU, additional research questions are provided for future research. (Minerva Anestesiol 2011;77:1099-107)
Original languageEnglish
Pages (from-to)1099-1107
JournalMinerva Anestesiologica
Issue number11
Publication statusPublished - Nov 2011


  • Delirium
  • Critical illness
  • Pediatrics
  • Intensive care
  • Child psychiatry

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