Patient preferences to value health outcomes in rheumatology clinical trials: Report from the OMERACT special interest group*

M. Thomas, L. Fraenkel, A. Boonen, N. Bansback, R. Buchbinder, D. Marshall, L. Proulx, M. Voshaar, P. Richards, D.P. Richards, M. Hiligsmann, F. Guillemin, B. Shea, P. Tugwell, G. Hazlewood*

*Corresponding author for this work

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Abstract

Objective: To inform a research plan for future studies by obtaining stakeholder input on the application of preference-based methods to clinical trial design. Methods: We conducted a virtual OMERACT session to encourage stakeholder engagement. We developed materials for the session to facilitate discussion based on identified case examples and feedback sessions. Results: Participants prioritized incorporating patient preferences in all aspects of trial design with an empha-sis on outcome selection. Participants highlighted the need for careful consideration around preference het-erogeneity and equity factors. Conclusion: Including patient preferences in trial design was considered a priority requiring further explora-tion to develop comprehensive guidance. (c) 2021 Elsevier Inc. All rights reserved.
Original languageEnglish
Pages (from-to)919-924
Number of pages6
JournalSeminars in Arthritis and Rheumatism
Volume51
Issue number4
DOIs
Publication statusPublished - 1 Aug 2021

Keywords

  • OMERACT
  • Patient preferences
  • Preference-based methods
  • Rheumatology
  • Clinical trials
  • Trade-offs

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