@article{1663ee6c3c034d04af04c9a25e4bccf2,
title = "Patient and diagnostic intervals of survivors of sarcoma: Results from the SURVSARC study",
abstract = "Background Patients diagnosed with sarcoma are hypothesized to experience a prolonged route to a cancer diagnosis. This route, the total interval, can be divided into a patient interval (the time from the appearance of symptoms to physician consultation) and diagnostic interval (time from the first consultation to diagnosis). In the current study, the authors investigated these intervals among survivors of sarcoma and identified factors associated with prolonged intervals. Methods A cross-sectional study was conducted among adult patients with sarcoma 2 to 10 years after diagnosis. Patients completed a questionnaire regarding their total interval, which was linked to clinical data from the Netherlands Cancer Registry. Descriptive statistics were used to describe intervals. Based on Dutch clinical guidelines, a diagnostic interval >= 1 month was considered to be prolonged and an interval >= 3 months was considered as very long. Multivariable regression analyses investigated associations between patient and tumor characteristics and interval length. Results A total of 1099 participants were included (response rate, 58%); approximately 60% reported a patient interval >= 1 month and 36% reported a patient interval >= 3 months. Risk factors for a very long patient interval were sarcoma of the skin or pelvis, liposarcoma, or rhabdomyosarcoma. Stage III disease was associated with a shorter patient interval. The diagnostic interval length was >= 1 month in 55% of patients and >= 3 months in 28% of patients. Risk factors for a very long diagnostic interval were female sex, age",
keywords = "cancer diagnosis, delay to diagnosis, diagnostic interval, diagnostic pathway, patient interval, sarcoma, survivorship, RISK-FACTORS, CANCER, OUTCOMES, PARTICIPATION, DESIGN, RATES, DELAY",
author = "Soomers, {Vicky L. M. N.} and Olga Husson and Desar, {Ingrid M. E.} and {van de Sande}, {Michiel A. J.} and {de Haan}, {Jacco J.} and Cornelis Verhoef and Vriens, {Ingeborg J. H.} and {van Houdt}, {Winan J.} and {van de Poll-franse}, Lonneke and {van der Graaf}, {Winette T. A.}",
note = "Funding Information: Vicky L. M. N. Soomers is supported by a junior research grant from the Radboud Institute of Health Sciences. Olga Husson is supported by a Social Psychology Fellowship from the Dutch Cancer Society (#KUN2015-7527) and a Netherlands Organization for Scientific Research VIDI grant (198.007). Michiel A. J. van de Sande has received a research grant from Daychi Sankyo for work performed outside of the current study. The other authors made no disclosures. The Patient Reported Outcomes Following Initial treatment and Long-term Evaluation of Survivorship (PROFILES) registry was funded by an Investment Grant Medium (#480-08-009) of the Netherlands Organization for Scientific Research. The current research was supported by an Investment Grant Large (2016/04981/ZONMW-91101002) of the Netherlands Organization for Scientific Research. Funding Information: The Patient Reported Outcomes Following Initial treatment and Long‐term Evaluation of Survivorship (PROFILES) registry was funded by an Investment Grant Medium (#480‐08‐009) of the Netherlands Organization for Scientific Research. The current research was supported by an Investment Grant Large (2016/04981/ZONMW‐91101002) of the Netherlands Organization for Scientific Research. Funding Information: Vicky L. M. N. Soomers is supported by a junior research grant from the Radboud Institute of Health Sciences. Olga Husson is supported by a Social Psychology Fellowship from the Dutch Cancer Society (#KUN2015‐7527) and a Netherlands Organization for Scientific Research VIDI grant (198.007). Michiel A. J. van de Sande has received a research grant from Daychi Sankyo for work performed outside of the current study. The other authors made no disclosures. Publisher Copyright: {\textcopyright} 2020 American Cancer Society",
year = "2020",
month = dec,
day = "15",
doi = "10.1002/cncr.33181",
language = "English",
volume = "126",
pages = "5283--5292",
journal = "Cancer",
issn = "0008-543X",
publisher = "Wiley",
number = "24",
}