Paradoxical trends in the management of vestibular schwannoma in the United States Clinical article

Tsz Lau, Raul Olivera, Timothy, Jr. Miller, Katheryne Downes, Christopher Danner, Harry R. van Loveren, Siviero Agazzi*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Recent natural history studies of vestibular schwannomas (VSs) suggest that most of these tumors do not grow. The impact of these new data on management trends in the US is currently unknown. The aim in the present study was to evaluate current trends in the treatment of VS in the US by analyzing a national cancer database.The Surveillance, Epidemiology, and End Results Program is a national database maintained by the National Cancer Institute representing 26% of the US population. Data from the database were downloaded using provided software. Cases were isolated based on histology codes and the site code. Data from 2004 to 2007 were included in the analysis. The number of patients undergoing resection was compared with the number treated with beam radiation and observation, based on tumor size.Three thousand six hundred fifty cases were identified in the database. Over the study period, management choices for VSs showed a significant change only for tumors with a diameter <2 cm. In this tumor category, a decrease in resection and an increase in radiation were observed, with observation showing a modest increase but remaining low at an average of 25%.Study data demonstrated a shift in the management of small VSs in the US between 2004 and 2007, with microsurgical removal giving way to radiation treatment and the overall rate for observation remaining low and stable. With recent literature suggesting that the majority of small tumors do not grow, the authors assert that VSs are being overtreated in the US.
Original languageEnglish
Pages (from-to)514-519
JournalJournal of Neurosurgery
Issue number3
Publication statusPublished - Sept 2012


  • acoustic neuroma
  • national treatment rate
  • vestibular schwannoma


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