Pan-cancer image-based detection of clinically actionable genetic alterations

Jakob Nikolas Kather; Lara R. Heij; Heike I. Grabsch; Chiara Loeffler; Amelie Echle; Hannah Sophie Muti; Jeremias Krause; Jan M. Niehues; Kai A. J. Sommer; Peter Bankhead; Loes F. S. Kooreman; Jefree J. Schulte; Nicole A. Cipriani; Roman D. Buelow; Peter Boor; Nadina Ortiz-Bruechle; Andrew M. Hanby; Valerie Speirs; Sara Kochanny; Akash Patnaik; Andrew Srisuwananukorn; Hermann Brenner; Michael Hoffmeister; Piet A. van den Brandt; Dirk Jaeger; Christian Trautwein; Alexander T. Pearson; Tom Luedde

doi:10.1038/s43018-020-0087-6

Pan-cancer image-based detection of clinically actionable genetic alterations

Jakob Nikolas Kather, Lara R. Heij, Heike I. Grabsch, Chiara Loeffler, Amelie Echle, Hannah Sophie Muti, Jeremias Krause, Jan M. Niehues, Kai A. J. Sommer, Peter Bankhead, Loes F. S. Kooreman, Jefree J. Schulte, Nicole A. Cipriani, Roman D. Buelow, Peter Boor, Nadina Ortiz-Bruechle, Andrew M. Hanby, Valerie Speirs, Sara Kochanny, Akash PatnaikAndrew Srisuwananukorn, Hermann Brenner, Michael Hoffmeister, Piet A. van den Brandt, Dirk Jaeger, Christian Trautwein, Alexander T. Pearson, Tom Luedde

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	789-799
Number of pages	28
Journal	Nature Cancer
Volume	1
Issue number	8
DOIs	https://doi.org/10.1038/s43018-020-0087-6
Publication status	Published - Aug 2020

Keywords

COMPREHENSIVE MOLECULAR CHARACTERIZATION
GENOMIC CHARACTERIZATION
COLORECTAL-CANCER
MUTATIONS
SUBTYPES
HEAD

Access to Document

10.1038/s43018-020-0087-6

Cite this

Kather, J. N., Heij, L. R., Grabsch, H. I., Loeffler, C., Echle, A., Muti, H. S., Krause, J., Niehues, J. M., Sommer, K. A. J., Bankhead, P., Kooreman, L. F. S., Schulte, J. J., Cipriani, N. A., Buelow, R. D., Boor, P., Ortiz-Bruechle, N., Hanby, A. M., Speirs, V., Kochanny, S., ... Luedde, T. (2020). Pan-cancer image-based detection of clinically actionable genetic alterations. Nature Cancer, 1(8), 789-799. https://doi.org/10.1038/s43018-020-0087-6

Kather, Jakob Nikolas ; Heij, Lara R. ; Grabsch, Heike I. ; Loeffler, Chiara ; Echle, Amelie ; Muti, Hannah Sophie ; Krause, Jeremias ; Niehues, Jan M. ; Sommer, Kai A. J. ; Bankhead, Peter ; Kooreman, Loes F. S. ; Schulte, Jefree J. ; Cipriani, Nicole A. ; Buelow, Roman D. ; Boor, Peter ; Ortiz-Bruechle, Nadina ; Hanby, Andrew M. ; Speirs, Valerie ; Kochanny, Sara ; Patnaik, Akash ; Srisuwananukorn, Andrew ; Brenner, Hermann ; Hoffmeister, Michael ; van den Brandt, Piet A. ; Jaeger, Dirk ; Trautwein, Christian ; Pearson, Alexander T. ; Luedde, Tom. / Pan-cancer image-based detection of clinically actionable genetic alterations. In: Nature Cancer. 2020 ; Vol. 1, No. 8. pp. 789-799.

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title = "Pan-cancer image-based detection of clinically actionable genetic alterations",

keywords = "COMPREHENSIVE MOLECULAR CHARACTERIZATION, GENOMIC CHARACTERIZATION, COLORECTAL-CANCER, MUTATIONS, SUBTYPES, HEAD",

author = "Kather, {Jakob Nikolas} and Heij, {Lara R.} and Grabsch, {Heike I.} and Chiara Loeffler and Amelie Echle and Muti, {Hannah Sophie} and Jeremias Krause and Niehues, {Jan M.} and Sommer, {Kai A. J.} and Peter Bankhead and Kooreman, {Loes F. S.} and Schulte, {Jefree J.} and Cipriani, {Nicole A.} and Buelow, {Roman D.} and Peter Boor and Nadina Ortiz-Bruechle and Hanby, {Andrew M.} and Valerie Speirs and Sara Kochanny and Akash Patnaik and Andrew Srisuwananukorn and Hermann Brenner and Michael Hoffmeister and {van den Brandt}, {Piet A.} and Dirk Jaeger and Christian Trautwein and Pearson, {Alexander T.} and Tom Luedde",

year = "2020",

month = aug,

doi = "10.1038/s43018-020-0087-6",

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Kather, JN, Heij, LR , Grabsch, HI, Loeffler, C, Echle, A, Muti, HS, Krause, J, Niehues, JM, Sommer, KAJ, Bankhead, P, Kooreman, LFS, Schulte, JJ, Cipriani, NA, Buelow, RD, Boor, P, Ortiz-Bruechle, N, Hanby, AM, Speirs, V, Kochanny, S, Patnaik, A, Srisuwananukorn, A, Brenner, H, Hoffmeister, M, van den Brandt, PA, Jaeger, D, Trautwein, C, Pearson, AT & Luedde, T 2020, 'Pan-cancer image-based detection of clinically actionable genetic alterations', Nature Cancer, vol. 1, no. 8, pp. 789-799. https://doi.org/10.1038/s43018-020-0087-6

Pan-cancer image-based detection of clinically actionable genetic alterations. / Kather, Jakob Nikolas; Heij, Lara R.; Grabsch, Heike I.; Loeffler, Chiara; Echle, Amelie; Muti, Hannah Sophie; Krause, Jeremias; Niehues, Jan M.; Sommer, Kai A. J.; Bankhead, Peter; Kooreman, Loes F. S.; Schulte, Jefree J.; Cipriani, Nicole A.; Buelow, Roman D.; Boor, Peter; Ortiz-Bruechle, Nadina; Hanby, Andrew M.; Speirs, Valerie; Kochanny, Sara; Patnaik, Akash; Srisuwananukorn, Andrew; Brenner, Hermann; Hoffmeister, Michael; van den Brandt, Piet A.; Jaeger, Dirk; Trautwein, Christian; Pearson, Alexander T.; Luedde, Tom.

In: Nature Cancer, Vol. 1, No. 8, 08.2020, p. 789-799.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Pan-cancer image-based detection of clinically actionable genetic alterations

AU - Kather, Jakob Nikolas

AU - Heij, Lara R.

AU - Grabsch, Heike I.

AU - Loeffler, Chiara

AU - Echle, Amelie

AU - Muti, Hannah Sophie

AU - Krause, Jeremias

AU - Niehues, Jan M.

AU - Sommer, Kai A. J.

AU - Bankhead, Peter

AU - Kooreman, Loes F. S.

AU - Schulte, Jefree J.

AU - Cipriani, Nicole A.

AU - Buelow, Roman D.

AU - Boor, Peter

AU - Ortiz-Bruechle, Nadina

AU - Hanby, Andrew M.

AU - Speirs, Valerie

AU - Kochanny, Sara

AU - Patnaik, Akash

AU - Srisuwananukorn, Andrew

AU - Brenner, Hermann

AU - Hoffmeister, Michael

AU - van den Brandt, Piet A.

AU - Jaeger, Dirk

AU - Trautwein, Christian

AU - Pearson, Alexander T.

AU - Luedde, Tom

PY - 2020/8

Y1 - 2020/8

KW - COMPREHENSIVE MOLECULAR CHARACTERIZATION

KW - GENOMIC CHARACTERIZATION

KW - COLORECTAL-CANCER

KW - MUTATIONS

KW - SUBTYPES

KW - HEAD

U2 - 10.1038/s43018-020-0087-6

DO - 10.1038/s43018-020-0087-6

M3 - Article

C2 - 33763651

VL - 1

SP - 789

EP - 799

JO - Nature Cancer

JF - Nature Cancer

SN - 2662-1347

IS - 8

ER -