Pan-cancer analysis of whole genomes

P.J. Campbell, G. Getz, J.O. Korbel, J.M. Stuart, J.L. Jennings, L.D. Stein, M.D. Perry, H.K. Nahal-Bose, B.F.F. Ouellette, C.H. Li, E. Rheinbay, G.P. Nielsen, D.C. Sgroi, C.L. Wu, W.C. Faquin, V. Deshpande, P.C. Boutros, A.J. Lazar, K.A. Hoadley, D.N. LouisL.J. Dursi, C.K. Yung, M.H. Bailey, G. Saksena, K.M. Raine, I. Buchhalter, K. Kleinheinz, M. Schlesner, J. Zhang, W. Wang, D.A. Wheeler, L. Ding, J.T. Simpson, B.D. O'Connor, S. Yakneen, K. Ellrott, N. Miyoshi, A.P. Butler, R. Royo, S.I. Shorser, M. Vazquez, T. Rausch, G. Tiao, S.M. Waszak, B. Rodriguez-Martin, S. Shringarpure, D.Y. Wu, G.M. Demidov, O. Delaneau, S. Hayashi, David Townend

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)82-93
Number of pages50
JournalNature
Volume578
Issue number7793
DOIs
Publication statusPublished - 6 Feb 2020

Keywords

  • comprehensive characterization
  • dna-damage
  • evolution
  • landscape
  • patterns
  • rearrangements
  • signatures
  • somatic mutations
  • systematic analysis
  • tert promoter mutations
  • SYSTEMATIC ANALYSIS
  • COMPREHENSIVE CHARACTERIZATION
  • TERT PROMOTER MUTATIONS
  • SIGNATURES
  • LANDSCAPE
  • DNA-DAMAGE
  • PATTERNS
  • REARRANGEMENTS
  • SOMATIC MUTATIONS
  • EVOLUTION

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