PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune-mediated disease

Xiaosong Liu, Tom Arfman, Kanin Wichapong, Chris P. M. Reutelingsperger, Jan Voorberg, Gerry A. F. Nicolaes*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)1607-1617
Number of pages11
JournalJournal of Thrombosis and Haemostasis
Volume19
Issue number7
DOIs
Publication statusPublished - Jul 2021

Keywords

  • cancer
  • citrullination
  • immune disease
  • NETosis
  • neutrophil extracellular traps (NETs)
  • PAD4
  • PAD4 inhibitors
  • protein arginine deiminase
  • rheumatoid arthritis (RA)
  • sepsis
  • thrombosis
  • PROMOTE THROMBIN GENERATION
  • EXTRACELLULAR DNA TRAPS
  • DEIMINASE TYPE-4 PAD4
  • PEPTIDYLARGININE-DEIMINASE
  • RHEUMATOID-ARTHRITIS
  • CHROMATIN DECONDENSATION
  • CITRULLINATED PROTEINS
  • HISTONE DEIMINATION
  • STRUCTURAL BASIS
  • INNATE IMMUNITY

Cite this