P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias

Jeroen J. Mooren; Sibel E. Gultekin; Jos M. J. A. A. Straetmans; Annick Haesevoets; Carine J. Peutz-Kootstra; Christian U. Huebbers; Hans P. Dienes; Ulrike Wieland; Frans C. S. Ramaekers; Bernd Kremer; Ernst-Jan M. Speel; Jens P. Klussmann

doi:10.1002/ijc.28534

P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias

Jeroen J. Mooren^*, Sibel E. Gultekin, Jos M. J. A. A. Straetmans, Annick Haesevoets, Carine J. Peutz-Kootstra, Christian U. Huebbers, Hans P. Dienes, Ulrike Wieland, Frans C. S. Ramaekers, Bernd Kremer, Ernst-Jan M. Speel, Jens P. Klussmann

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

46 Citations (Web of Science)

Original language	English
Pages (from-to)	2108-2117
Journal	International Journal of Cancer
Volume	134
Issue number	9
DOIs	https://doi.org/10.1002/ijc.28534
Publication status	Published - 1 May 2014

Keywords

human papillomavirus
immunohistochemistry
FISH
PCR

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10.1002/ijc.28534

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Mooren, J. J., Gultekin, S. E., Straetmans, J. M. J. A. A., Haesevoets, A., Peutz-Kootstra, C. J., Huebbers, C. U., Dienes, H. P., Wieland, U., Ramaekers, F. C. S., Kremer, B., Speel, E-J. M., & Klussmann, J. P. (2014). P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias. International Journal of Cancer, 134(9), 2108-2117. https://doi.org/10.1002/ijc.28534

Mooren, Jeroen J. ; Gultekin, Sibel E. ; Straetmans, Jos M. J. A. A. ; Haesevoets, Annick ; Peutz-Kootstra, Carine J. ; Huebbers, Christian U. ; Dienes, Hans P. ; Wieland, Ulrike ; Ramaekers, Frans C. S. ; Kremer, Bernd ; Speel, Ernst-Jan M. ; Klussmann, Jens P. / P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias. In: International Journal of Cancer. 2014 ; Vol. 134, No. 9. pp. 2108-2117.

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title = "P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias",

keywords = "human papillomavirus, immunohistochemistry, FISH, PCR",

author = "Mooren, {Jeroen J.} and Gultekin, {Sibel E.} and Straetmans, {Jos M. J. A. A.} and Annick Haesevoets and Peutz-Kootstra, {Carine J.} and Huebbers, {Christian U.} and Dienes, {Hans P.} and Ulrike Wieland and Ramaekers, {Frans C. S.} and Bernd Kremer and Speel, {Ernst-Jan M.} and Klussmann, {Jens P.}",

year = "2014",

month = may,

day = "1",

doi = "10.1002/ijc.28534",

language = "English",

volume = "134",

pages = "2108--2117",

journal = "International Journal of Cancer",

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Mooren, JJ, Gultekin, SE, Straetmans, JMJAA, Haesevoets, A , Peutz-Kootstra, CJ, Huebbers, CU, Dienes, HP, Wieland, U, Ramaekers, FCS, Kremer, B , Speel, E-JM & Klussmann, JP 2014, 'P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias', International Journal of Cancer, vol. 134, no. 9, pp. 2108-2117. https://doi.org/10.1002/ijc.28534

P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias. / Mooren, Jeroen J.; Gultekin, Sibel E.; Straetmans, Jos M. J. A. A.; Haesevoets, Annick ; Peutz-Kootstra, Carine J.; Huebbers, Christian U.; Dienes, Hans P.; Wieland, Ulrike; Ramaekers, Frans C. S.; Kremer, Bernd ; Speel, Ernst-Jan M.; Klussmann, Jens P.

In: International Journal of Cancer, Vol. 134, No. 9, 01.05.2014, p. 2108-2117.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias

AU - Mooren, Jeroen J.

AU - Gultekin, Sibel E.

AU - Straetmans, Jos M. J. A. A.

AU - Haesevoets, Annick

AU - Peutz-Kootstra, Carine J.

AU - Huebbers, Christian U.

AU - Dienes, Hans P.

AU - Wieland, Ulrike

AU - Ramaekers, Frans C. S.

AU - Kremer, Bernd

AU - Speel, Ernst-Jan M.

AU - Klussmann, Jens P.

PY - 2014/5/1

Y1 - 2014/5/1

KW - human papillomavirus

KW - immunohistochemistry

KW - FISH

KW - PCR

U2 - 10.1002/ijc.28534

DO - 10.1002/ijc.28534

M3 - Article

C2 - 24127203

VL - 134

SP - 2108

EP - 2117

JO - International Journal of Cancer

JF - International Journal of Cancer

SN - 0020-7136

IS - 9

ER -

Mooren JJ, Gultekin SE, Straetmans JMJAA, Haesevoets A , Peutz-Kootstra CJ, Huebbers CU et al. P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias. International Journal of Cancer. 2014 May 1;134(9):2108-2117. https://doi.org/10.1002/ijc.28534