Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery

Maartje H M Segers; Anders Behndig; Frank J H M van den Biggelaar; Lucia Brocato; Ype P Henry; Rudy M M A Nuijts; Paul Rosen; Marie-Jose Tassignon; David Young; Ulf Stenevi; Mats Lundstrom; Mor M Dickman

doi:10.1097/j.jcrs.0000000000000901

Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery

Maartje H M Segers
, Anders Behndig
, Frank J H M van den Biggelaar
, Lucia Brocato
, Ype P Henry
, Rudy M M A Nuijts
, Paul Rosen
, Marie-Jose Tassignon
, David Young
, Ulf Stenevi
, Mats Lundstrom
, Mor M Dickman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

PURPOSE: To analyze the outcomes of cataract surgery complicated by posterior capsule rupture (PCR).

SETTING: European clinics affiliated to the European Registry of Quality Outcomes for Cataract and Refractive Surgery (EUREQUO).

DESIGN: Retrospective cross-sectional register-based study.

METHODS: Data was retrieved from the EUREQUO between January 1, 2008, and December 31, 2018. The database consists of demographics, intraoperative complications, including PCR, type of intraocular lens (IOL) material, postoperative refraction, corrected distance visual acuity (CDVA), and postoperative complications.

RESULTS: 1,371,743 cataract extractions with complete postoperative data were reported in the EUREQUO. In 12,196 cases (0.9%), a PCR was reported. Following PCR, patients were more likely to receive a PMMA IOL (5.2% vs. 0.4%, respectively) or no IOL (1.1% vs. 0.02%, respectively) compared to patients without PCR. The refractive and visual outcomes following PCR were significantly worse than without PCR (mean CDVA 0.13+/-0.21 versus 0.05+/-0.16 logMAR, P<0.001, mean absolute biometry prediction error 1.15+/-1.60 diopters (D) versus 0.41+/-0.45D, P<0.001). Multivariable linear regression analysis, adjusting for potential explanatory variables, confirmed a statistically significant difference (0.04 logMAR, P<0.001 and 0.70D, P<0.001, respectively). Patients with PCR had significantly more postoperative complications (corneal edema 0.88% vs. 0.17%, adjusted odds ratio (aOR) 2.80 95%CI 2.27-3.45, endophthalmitis 0.11% vs. 0.02%, aOR 4.40 95%CI2.48-7.81, uncontrolled intraocular pressure 0.55% vs. 0.03%, aOR 14.58 95%CI11.16-19.06, P<0.001).

CONCLUSION: Patients with PCR have significantly worse visual and refractive outcomes and more postoperative complications than patients without PCR. However, the vast majority of these patients achieved better postoperative visual acuity than before surgery.

Original language	English
Pages (from-to)	942-946
Number of pages	5
Journal	Journal of Cataract and Refractive Surgery
Volume	48
Issue number	8
Early online date	1 Feb 2022
DOIs	https://doi.org/10.1097/j.jcrs.0000000000000901
Publication status	Published - Aug 2022

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10.1097/j.jcrs.0000000000000901

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Segers, M. H. M., Behndig, A., van den Biggelaar, F. J. H. M., Brocato, L., Henry, Y. P., Nuijts, R. M. M. A., Rosen, P., Tassignon, M.-J., Young, D., Stenevi, U., Lundstrom, M., & Dickman, M. M. (2022). Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery. Journal of Cataract and Refractive Surgery, 48(8), 942-946. https://doi.org/10.1097/j.jcrs.0000000000000901

@article{44174896859540b4a3d0d91c20bc87dc,

title = "Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery",

abstract = "PURPOSE: To analyze the outcomes of cataract surgery complicated by posterior capsule rupture (PCR).SETTING: European clinics affiliated to the European Registry of Quality Outcomes for Cataract and Refractive Surgery (EUREQUO).DESIGN: Retrospective cross-sectional register-based study.METHODS: Data was retrieved from the EUREQUO between January 1, 2008, and December 31, 2018. The database consists of demographics, intraoperative complications, including PCR, type of intraocular lens (IOL) material, postoperative refraction, corrected distance visual acuity (CDVA), and postoperative complications.RESULTS: 1,371,743 cataract extractions with complete postoperative data were reported in the EUREQUO. In 12,196 cases (0.9\%), a PCR was reported. Following PCR, patients were more likely to receive a PMMA IOL (5.2\% vs. 0.4\%, respectively) or no IOL (1.1\% vs. 0.02\%, respectively) compared to patients without PCR. The refractive and visual outcomes following PCR were significantly worse than without PCR (mean CDVA 0.13+/-0.21 versus 0.05+/-0.16 logMAR, P<0.001, mean absolute biometry prediction error 1.15+/-1.60 diopters (D) versus 0.41+/-0.45D, P<0.001). Multivariable linear regression analysis, adjusting for potential explanatory variables, confirmed a statistically significant difference (0.04 logMAR, P<0.001 and 0.70D, P<0.001, respectively). Patients with PCR had significantly more postoperative complications (corneal edema 0.88\% vs. 0.17\%, adjusted odds ratio (aOR) 2.80 95\%CI 2.27-3.45, endophthalmitis 0.11\% vs. 0.02\%, aOR 4.40 95\%CI2.48-7.81, uncontrolled intraocular pressure 0.55\% vs. 0.03\%, aOR 14.58 95\%CI11.16-19.06, P<0.001).CONCLUSION: Patients with PCR have significantly worse visual and refractive outcomes and more postoperative complications than patients without PCR. However, the vast majority of these patients achieved better postoperative visual acuity than before surgery.",

author = "Segers, \{Maartje H M\} and Anders Behndig and \{van den Biggelaar\}, \{Frank J H M\} and Lucia Brocato and Henry, \{Ype P\} and Nuijts, \{Rudy M M A\} and Paul Rosen and Marie-Jose Tassignon and David Young and Ulf Stenevi and Mats Lundstrom and Dickman, \{Mor M\}",

year = "2022",

month = aug,

doi = "10.1097/j.jcrs.0000000000000901",

language = "English",

volume = "48",

pages = "942--946",

journal = "Journal of Cataract and Refractive Surgery",

issn = "0886-3350",

publisher = "Lippincott Williams \& Wilkins",

number = "8",

}

Segers, MHM, Behndig, A, van den Biggelaar, FJHM, Brocato, L, Henry, YP, Nuijts, RMMA, Rosen, P, Tassignon, M-J, Young, D, Stenevi, U, Lundstrom, M & Dickman, MM 2022, 'Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery', Journal of Cataract and Refractive Surgery, vol. 48, no. 8, pp. 942-946. https://doi.org/10.1097/j.jcrs.0000000000000901

Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery. / Segers, Maartje H M; Behndig, Anders; van den Biggelaar, Frank J H M et al.
In: Journal of Cataract and Refractive Surgery, Vol. 48, No. 8, 08.2022, p. 942-946.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery

AU - Segers, Maartje H M

AU - Behndig, Anders

AU - van den Biggelaar, Frank J H M

AU - Brocato, Lucia

AU - Henry, Ype P

AU - Nuijts, Rudy M M A

AU - Rosen, Paul

AU - Tassignon, Marie-Jose

AU - Young, David

AU - Stenevi, Ulf

AU - Lundstrom, Mats

AU - Dickman, Mor M

PY - 2022/8

Y1 - 2022/8

N2 - PURPOSE: To analyze the outcomes of cataract surgery complicated by posterior capsule rupture (PCR).SETTING: European clinics affiliated to the European Registry of Quality Outcomes for Cataract and Refractive Surgery (EUREQUO).DESIGN: Retrospective cross-sectional register-based study.METHODS: Data was retrieved from the EUREQUO between January 1, 2008, and December 31, 2018. The database consists of demographics, intraoperative complications, including PCR, type of intraocular lens (IOL) material, postoperative refraction, corrected distance visual acuity (CDVA), and postoperative complications.RESULTS: 1,371,743 cataract extractions with complete postoperative data were reported in the EUREQUO. In 12,196 cases (0.9%), a PCR was reported. Following PCR, patients were more likely to receive a PMMA IOL (5.2% vs. 0.4%, respectively) or no IOL (1.1% vs. 0.02%, respectively) compared to patients without PCR. The refractive and visual outcomes following PCR were significantly worse than without PCR (mean CDVA 0.13+/-0.21 versus 0.05+/-0.16 logMAR, P<0.001, mean absolute biometry prediction error 1.15+/-1.60 diopters (D) versus 0.41+/-0.45D, P<0.001). Multivariable linear regression analysis, adjusting for potential explanatory variables, confirmed a statistically significant difference (0.04 logMAR, P<0.001 and 0.70D, P<0.001, respectively). Patients with PCR had significantly more postoperative complications (corneal edema 0.88% vs. 0.17%, adjusted odds ratio (aOR) 2.80 95%CI 2.27-3.45, endophthalmitis 0.11% vs. 0.02%, aOR 4.40 95%CI2.48-7.81, uncontrolled intraocular pressure 0.55% vs. 0.03%, aOR 14.58 95%CI11.16-19.06, P<0.001).CONCLUSION: Patients with PCR have significantly worse visual and refractive outcomes and more postoperative complications than patients without PCR. However, the vast majority of these patients achieved better postoperative visual acuity than before surgery.

AB - PURPOSE: To analyze the outcomes of cataract surgery complicated by posterior capsule rupture (PCR).SETTING: European clinics affiliated to the European Registry of Quality Outcomes for Cataract and Refractive Surgery (EUREQUO).DESIGN: Retrospective cross-sectional register-based study.METHODS: Data was retrieved from the EUREQUO between January 1, 2008, and December 31, 2018. The database consists of demographics, intraoperative complications, including PCR, type of intraocular lens (IOL) material, postoperative refraction, corrected distance visual acuity (CDVA), and postoperative complications.RESULTS: 1,371,743 cataract extractions with complete postoperative data were reported in the EUREQUO. In 12,196 cases (0.9%), a PCR was reported. Following PCR, patients were more likely to receive a PMMA IOL (5.2% vs. 0.4%, respectively) or no IOL (1.1% vs. 0.02%, respectively) compared to patients without PCR. The refractive and visual outcomes following PCR were significantly worse than without PCR (mean CDVA 0.13+/-0.21 versus 0.05+/-0.16 logMAR, P<0.001, mean absolute biometry prediction error 1.15+/-1.60 diopters (D) versus 0.41+/-0.45D, P<0.001). Multivariable linear regression analysis, adjusting for potential explanatory variables, confirmed a statistically significant difference (0.04 logMAR, P<0.001 and 0.70D, P<0.001, respectively). Patients with PCR had significantly more postoperative complications (corneal edema 0.88% vs. 0.17%, adjusted odds ratio (aOR) 2.80 95%CI 2.27-3.45, endophthalmitis 0.11% vs. 0.02%, aOR 4.40 95%CI2.48-7.81, uncontrolled intraocular pressure 0.55% vs. 0.03%, aOR 14.58 95%CI11.16-19.06, P<0.001).CONCLUSION: Patients with PCR have significantly worse visual and refractive outcomes and more postoperative complications than patients without PCR. However, the vast majority of these patients achieved better postoperative visual acuity than before surgery.

U2 - 10.1097/j.jcrs.0000000000000901

DO - 10.1097/j.jcrs.0000000000000901

M3 - Article

C2 - 35179858

SN - 0886-3350

VL - 48

SP - 942

EP - 946

JO - Journal of Cataract and Refractive Surgery

JF - Journal of Cataract and Refractive Surgery

IS - 8

ER -

Outcomes of cataract surgery complicated by posterior capsule rupture in the European Registry of Quality Outcomes for Cataract and Refractive Surgery

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