Outcomes for COPD pharmacological trials: from lung function to biomarkers

M. Cazzola; W. MacNee; F.J. Martinez; K.F. Rabe; L.G. Franciosi; P.J. Barnes; V. Brusasco; P.S. Burge; P.M. Calverley; B.R. Celli; P.W. Jones; D.A. Mahler; B. Make; M. Miravitlles; C.P. Page; P. Palange; D. Parr; M. Pistolesi; S.I. Rennard; M.P.M.H. Rutten-van Mölken; R. Stockley; S.D. Sullivan; J.A. Wedzicha; E.F. Wouters

doi:10.1183/09031936.00099306

Outcomes for COPD pharmacological trials: from lung function to biomarkers

M. Cazzola^*, W. MacNee, F.J. Martinez, K.F. Rabe, L.G. Franciosi, P.J. Barnes, V. Brusasco, P.S. Burge, P.M. Calverley, B.R. Celli, P.W. Jones, D.A. Mahler, B. Make, M. Miravitlles, C.P. Page, P. Palange, D. Parr, M. Pistolesi, S.I. Rennard, M.P.M.H. Rutten-van MölkenR. Stockley, S.D. Sullivan, J.A. Wedzicha, E.F. Wouters

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.

Original language	English
Pages (from-to)	416-69
Journal	European Respiratory Journal
Volume	31
Issue number	2
DOIs	https://doi.org/10.1183/09031936.00099306
Publication status	Published - 1 Jan 2008

Access to Document

10.1183/09031936.00099306

Cite this

Cazzola, M., MacNee, W., Martinez, F. J., Rabe, K. F., Franciosi, L. G., Barnes, P. J., Brusasco, V., Burge, P. S., Calverley, P. M., Celli, B. R., Jones, P. W., Mahler, D. A., Make, B., Miravitlles, M., Page, C. P., Palange, P., Parr, D., Pistolesi, M., Rennard, S. I., ... Wouters, E. F. (2008). Outcomes for COPD pharmacological trials: from lung function to biomarkers. European Respiratory Journal, 31(2), 416-69. https://doi.org/10.1183/09031936.00099306

@article{f5c3a604d93443f28a9d997610f952cd,

title = "Outcomes for COPD pharmacological trials: from lung function to biomarkers",

abstract = "The American Thoracic Society/European Respiratory Society jointly created a Task Force on {"}Outcomes for COPD pharmacological trials: from lung function to biomarkers{"} to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.",

author = "M. Cazzola and W. MacNee and F.J. Martinez and K.F. Rabe and L.G. Franciosi and P.J. Barnes and V. Brusasco and P.S. Burge and P.M. Calverley and B.R. Celli and P.W. Jones and D.A. Mahler and B. Make and M. Miravitlles and C.P. Page and P. Palange and D. Parr and M. Pistolesi and S.I. Rennard and {Rutten-van M{\"o}lken}, M.P.M.H. and R. Stockley and S.D. Sullivan and J.A. Wedzicha and E.F. Wouters",

year = "2008",

month = jan,

day = "1",

doi = "10.1183/09031936.00099306",

language = "English",

volume = "31",

pages = "416--69",

journal = "European Respiratory Journal",

issn = "0903-1936",

publisher = "European Respiratory Society",

number = "2",

}

Cazzola, M, MacNee, W, Martinez, FJ, Rabe, KF, Franciosi, LG, Barnes, PJ, Brusasco, V, Burge, PS, Calverley, PM, Celli, BR, Jones, PW, Mahler, DA, Make, B, Miravitlles, M, Page, CP, Palange, P, Parr, D, Pistolesi, M, Rennard, SI, Rutten-van Mölken, MPMH, Stockley, R, Sullivan, SD, Wedzicha, JA & Wouters, EF 2008, 'Outcomes for COPD pharmacological trials: from lung function to biomarkers', European Respiratory Journal, vol. 31, no. 2, pp. 416-69. https://doi.org/10.1183/09031936.00099306

TY - JOUR

T1 - Outcomes for COPD pharmacological trials: from lung function to biomarkers

AU - Cazzola, M.

AU - MacNee, W.

AU - Martinez, F.J.

AU - Rabe, K.F.

AU - Franciosi, L.G.

AU - Barnes, P.J.

AU - Brusasco, V.

AU - Burge, P.S.

AU - Calverley, P.M.

AU - Celli, B.R.

AU - Jones, P.W.

AU - Mahler, D.A.

AU - Make, B.

AU - Miravitlles, M.

AU - Page, C.P.

AU - Palange, P.

AU - Parr, D.

AU - Pistolesi, M.

AU - Rennard, S.I.

AU - Rutten-van Mölken, M.P.M.H.

AU - Stockley, R.

AU - Sullivan, S.D.

AU - Wedzicha, J.A.

AU - Wouters, E.F.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.

AB - The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.

U2 - 10.1183/09031936.00099306

DO - 10.1183/09031936.00099306

M3 - Article

C2 - 18238951

SN - 0903-1936

VL - 31

SP - 416

EP - 469

JO - European Respiratory Journal

JF - European Respiratory Journal

IS - 2

ER -