Outcomes for COPD pharmacological trials: from lung function to biomarkers

M. Cazzola, W. MacNee, F.J. Martinez, K.F. Rabe, L.G. Franciosi, P.J. Barnes, V. Brusasco, P.S. Burge, P.M. Calverley, B.R. Celli, P.W. Jones, D.A. Mahler, B. Make, M. Miravitlles, C.P. Page, P. Palange, D. Parr, M. Pistolesi, S.I. Rennard, M.P.M.H. Rutten-van MölkenR. Stockley, S.D. Sullivan, J.A. Wedzicha, E.F. Wouters

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    Abstract

    The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.
    Original languageEnglish
    Pages (from-to)416-69
    JournalEuropean Respiratory Journal
    Volume31
    Issue number2
    DOIs
    Publication statusPublished - 1 Jan 2008

    Cite this

    Cazzola, M., MacNee, W., Martinez, F. J., Rabe, K. F., Franciosi, L. G., Barnes, P. J., Brusasco, V., Burge, P. S., Calverley, P. M., Celli, B. R., Jones, P. W., Mahler, D. A., Make, B., Miravitlles, M., Page, C. P., Palange, P., Parr, D., Pistolesi, M., Rennard, S. I., ... Wouters, E. F. (2008). Outcomes for COPD pharmacological trials: from lung function to biomarkers. European Respiratory Journal, 31(2), 416-69. https://doi.org/10.1183/09031936.00099306