Outcomes for COPD pharmacological trials: from lung function to biomarkers

M. Cazzola; W. MacNee; F.J. Martinez; K.F. Rabe; L.G. Franciosi; P.J. Barnes; V. Brusasco; P.S. Burge; P.M. Calverley; B.R. Celli; P.W. Jones; D.A. Mahler; B. Make; M. Miravitlles; C.P. Page; P. Palange; D. Parr; M. Pistolesi; S.I. Rennard; M.P.M.H. Rutten-van Mölken; R. Stockley; S.D. Sullivan; J.A. Wedzicha; E.F. Wouters

doi:10.1183/09031936.00099306

Outcomes for COPD pharmacological trials: from lung function to biomarkers

M. Cazzola^*, W. MacNee, F.J. Martinez, K.F. Rabe, L.G. Franciosi, P.J. Barnes, V. Brusasco, P.S. Burge, P.M. Calverley, B.R. Celli, P.W. Jones, D.A. Mahler, B. Make, M. Miravitlles, C.P. Page, P. Palange, D. Parr, M. Pistolesi, S.I. Rennard, M.P.M.H. Rutten-van MölkenR. Stockley, S.D. Sullivan, J.A. Wedzicha, E.F. Wouters

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.

Original language	English
Pages (from-to)	416-69
Journal	European Respiratory Journal
Volume	31
Issue number	2
DOIs	https://doi.org/10.1183/09031936.00099306
Publication status	Published - 1 Jan 2008

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10.1183/09031936.00099306

Cite this

Cazzola, M., MacNee, W., Martinez, F. J., Rabe, K. F., Franciosi, L. G., Barnes, P. J., Brusasco, V., Burge, P. S., Calverley, P. M., Celli, B. R., Jones, P. W., Mahler, D. A., Make, B., Miravitlles, M., Page, C. P., Palange, P., Parr, D., Pistolesi, M., Rennard, S. I., ... Wouters, E. F. (2008). Outcomes for COPD pharmacological trials: from lung function to biomarkers. European Respiratory Journal, 31(2), 416-69. https://doi.org/10.1183/09031936.00099306

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abstract = "The American Thoracic Society/European Respiratory Society jointly created a Task Force on {"}Outcomes for COPD pharmacological trials: from lung function to biomarkers{"} to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.",

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Cazzola, M, MacNee, W, Martinez, FJ, Rabe, KF, Franciosi, LG, Barnes, PJ, Brusasco, V, Burge, PS, Calverley, PM, Celli, BR, Jones, PW, Mahler, DA, Make, B, Miravitlles, M, Page, CP, Palange, P, Parr, D, Pistolesi, M, Rennard, SI, Rutten-van Mölken, MPMH, Stockley, R, Sullivan, SD, Wedzicha, JA & Wouters, EF 2008, 'Outcomes for COPD pharmacological trials: from lung function to biomarkers', European Respiratory Journal, vol. 31, no. 2, pp. 416-69. https://doi.org/10.1183/09031936.00099306

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AU - MacNee, W.

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AU - Franciosi, L.G.

AU - Barnes, P.J.

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AU - Calverley, P.M.

AU - Celli, B.R.

AU - Jones, P.W.

AU - Mahler, D.A.

AU - Make, B.

AU - Miravitlles, M.

AU - Page, C.P.

AU - Palange, P.

AU - Parr, D.

AU - Pistolesi, M.

AU - Rennard, S.I.

AU - Rutten-van Mölken, M.P.M.H.

AU - Stockley, R.

AU - Sullivan, S.D.

AU - Wedzicha, J.A.

AU - Wouters, E.F.

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