TY - JOUR
T1 - Outcome Priorities for Older Persons With Sarcopenia
AU - Hiligsmann, Mickael
AU - Beaudart, Charlotte
AU - Bruyere, Olivier
AU - Biver, Emmanuel
AU - Bauer, Juergen
AU - Cruz-Jentoft, Alfonso J.
AU - Gesmundo, Antonella
AU - Goisser, Sabine
AU - Landi, Francesco
AU - Locquet, Medea
AU - Maggi, Stefania
AU - Rizzoli, Rene
AU - Rolland, Yves
AU - Vaquero, Nieves
AU - Cooper, Cyrus
AU - Reginster, Jean-Yves
AU - European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
N1 - Funding Information:
This work was supported by the European Society for Clinical and Economic Aspects of Osteoporosis,Osteoarthritis and Musculoskeletal Diseases (ESCEO).
Funding Information:
The study was conducted in 6 European countries (between November 2017 and December 2018) in community-dwelling persons 65 years of age and older with sarcopenia and visiting the clinic. Sarcopenia was diagnosed according to valid published definitions [ie, those by the European Working Group on Sarcopenia in Older People (EWGSOP), Foundation for the National Institutes of Health (FNIH), and International Working Group on Sarcopenia (IWGS)]. 10–12 Only participants who were cognitively able to understand and fill out the questionnaire were included. The questionnaire was completed by the participant at the clinic or at home. In line with common rules of thumb for minimum sample size, 13 a minimum of 200 respondents were targeted. Approval for this study was obtained from the Medical Ethics Committee of the University of Liège, which coordinated the project, and in participating centers that required ethics approval for a DCE questionnaire study.
Publisher Copyright:
© 2019 AMDA – The Society for Post-Acute and Long-Term Care Medicine
PY - 2020/2
Y1 - 2020/2
N2 - Objectives: To evaluate patients' preferences for sarcopenia outcomes.Design: Discrete-choice experiment (DCE)Setting and Participants: Community-dwelling individuals older than 65 years suffering from sarcopenia recruited in Belgium, France, Germany, Italy, Spain, and Switzerland, who visited the clinic and were cognitively able to understand and fill out the survey.Methods: In the DCE survey, participants were repetitively asked to choose which one of the 2 patients suffering from sarcopenia deserves treatment the most. The 2 patients presented different levels of risk for 5 preselected sarcopenia outcomes: quality of life, mobility, domestic activities, fatigue, and falls. The DCE included 12 choice sets. Mixed logit panel model was used to estimate patients preferences and latent class model was conducted to identify profiles of responses.Results: A total of 216 sarcopenic persons were included for the analysis (68% women; mean age 78 years). All 5 preselected sarcopenia outcomes were shown to be significant. Overall, the most important sarcopenia outcome was mobility (30%), followed by the ability to manage domestic activities (22%), the risk of falls (18%), fatigue (17%), and quality of life (14%). The latent class model identified 2 classes of respondents. In the first class (probability of 56%), participants valued mobility the most (42%), followed by the ability to manage domestic activities (23%) and risk of falls (17%). In the second class, fatigue was the most important outcome (27%) followed by domestic activities (19%) and risk of falls (19%). No statistically significant associations between the latent classes and sociodemographic characteristics were found.Conclusions and Implications: This study suggests that all 5 preselected outcomes were important for sarcopenic older individuals. Overall, the most important outcomes were mobility and the ability to manage domestic activities, although variations in preferences were observed between respondents. This could help in incorporating patient preferences when designing appropriate solutions for individuals with sarcopenia. (C) 2019 The Author(s). Published by Elsevier Inc. on behalf of AMDA - The Society for Post-Acute and Long-Term Care Medicine. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
AB - Objectives: To evaluate patients' preferences for sarcopenia outcomes.Design: Discrete-choice experiment (DCE)Setting and Participants: Community-dwelling individuals older than 65 years suffering from sarcopenia recruited in Belgium, France, Germany, Italy, Spain, and Switzerland, who visited the clinic and were cognitively able to understand and fill out the survey.Methods: In the DCE survey, participants were repetitively asked to choose which one of the 2 patients suffering from sarcopenia deserves treatment the most. The 2 patients presented different levels of risk for 5 preselected sarcopenia outcomes: quality of life, mobility, domestic activities, fatigue, and falls. The DCE included 12 choice sets. Mixed logit panel model was used to estimate patients preferences and latent class model was conducted to identify profiles of responses.Results: A total of 216 sarcopenic persons were included for the analysis (68% women; mean age 78 years). All 5 preselected sarcopenia outcomes were shown to be significant. Overall, the most important sarcopenia outcome was mobility (30%), followed by the ability to manage domestic activities (22%), the risk of falls (18%), fatigue (17%), and quality of life (14%). The latent class model identified 2 classes of respondents. In the first class (probability of 56%), participants valued mobility the most (42%), followed by the ability to manage domestic activities (23%) and risk of falls (17%). In the second class, fatigue was the most important outcome (27%) followed by domestic activities (19%) and risk of falls (19%). No statistically significant associations between the latent classes and sociodemographic characteristics were found.Conclusions and Implications: This study suggests that all 5 preselected outcomes were important for sarcopenic older individuals. Overall, the most important outcomes were mobility and the ability to manage domestic activities, although variations in preferences were observed between respondents. This could help in incorporating patient preferences when designing appropriate solutions for individuals with sarcopenia. (C) 2019 The Author(s). Published by Elsevier Inc. on behalf of AMDA - The Society for Post-Acute and Long-Term Care Medicine. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
KW - Discrete-choice experiment
KW - sarcopenia
KW - outcomes
KW - patient preferences
KW - DISCRETE-CHOICE EXPERIMENTS
KW - HEALTH
KW - QUALITY
KW - BURDEN
U2 - 10.1016/j.jamda.2019.08.026
DO - 10.1016/j.jamda.2019.08.026
M3 - Article
C2 - 31672566
SN - 1525-8610
VL - 21
SP - 267-271.e2
JO - Journal of the American Medical Directors Association
JF - Journal of the American Medical Directors Association
IS - 2
ER -