Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib

Viola Denzinger; Kristina Busygina; Janina Jamasbi; Isabell Pekrul; Michael Spannagl; Christian Weber; Reinhard Lorenz; Wolfgang Siess

doi:10.1055/s-0039-1677744

Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib

Viola Denzinger, Kristina Busygina, Janina Jamasbi, Isabell Pekrul, Michael Spannagl, Christian Weber, Reinhard Lorenz, Wolfgang Siess^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	397-406
Number of pages	10
Journal	Thrombosis and Haemostasis
Volume	119
Issue number	3
DOIs	https://doi.org/10.1055/s-0039-1677744
Publication status	Published - Mar 2019

Keywords

Btk inhibitor
platelet aggregation
bleeding
PFA
GPVI
TYROSINE KINASE INHIBITOR
GLYCOPROTEIN VI BINDS
TERM-FOLLOW-UP
THROMBUS FORMATION
TARGETING BTK
ACTIVATION
AGGREGATION
COLLAGEN
SINGLE
PLAQUE

Access to Document

10.1055/s-0039-1677744

Cite this

Denzinger, V., Busygina, K., Jamasbi, J., Pekrul, I., Spannagl, M., Weber, C., Lorenz, R., & Siess, W. (2019). Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. Thrombosis and Haemostasis, 119(3), 397-406. https://doi.org/10.1055/s-0039-1677744

Denzinger, Viola ; Busygina, Kristina ; Jamasbi, Janina ; Pekrul, Isabell ; Spannagl, Michael ; Weber, Christian ; Lorenz, Reinhard ; Siess, Wolfgang. / Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. In: Thrombosis and Haemostasis. 2019 ; Vol. 119, No. 3. pp. 397-406.

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keywords = "Btk inhibitor, platelet aggregation, bleeding, PFA, GPVI, TYROSINE KINASE INHIBITOR, GLYCOPROTEIN VI BINDS, TERM-FOLLOW-UP, THROMBUS FORMATION, TARGETING BTK, ACTIVATION, AGGREGATION, COLLAGEN, SINGLE, PLAQUE",

author = "Viola Denzinger and Kristina Busygina and Janina Jamasbi and Isabell Pekrul and Michael Spannagl and Christian Weber and Reinhard Lorenz and Wolfgang Siess",

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Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. / Denzinger, Viola; Busygina, Kristina; Jamasbi, Janina; Pekrul, Isabell; Spannagl, Michael; Weber, Christian; Lorenz, Reinhard; Siess, Wolfgang.

In: Thrombosis and Haemostasis, Vol. 119, No. 3, 03.2019, p. 397-406.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib

AU - Denzinger, Viola

AU - Busygina, Kristina

AU - Jamasbi, Janina

AU - Pekrul, Isabell

AU - Spannagl, Michael

AU - Weber, Christian

AU - Lorenz, Reinhard

AU - Siess, Wolfgang

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KW - bleeding

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KW - TYROSINE KINASE INHIBITOR

KW - GLYCOPROTEIN VI BINDS

KW - TERM-FOLLOW-UP

KW - THROMBUS FORMATION

KW - TARGETING BTK

KW - ACTIVATION

KW - AGGREGATION

KW - COLLAGEN

KW - SINGLE

KW - PLAQUE

U2 - 10.1055/s-0039-1677744

DO - 10.1055/s-0039-1677744

M3 - Article

VL - 119

SP - 397

EP - 406

JO - Thrombosis and Haemostasis

JF - Thrombosis and Haemostasis

SN - 0340-6245

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ER -