Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer

Jessica J. Cunningham*, Joel S. Brown, Robert A. Gatenby, Katerina Stankova

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)67-78
Number of pages12
JournalJournal of Theoretical Biology
Volume459
DOIs
Publication statusPublished - 14 Dec 2018

Keywords

  • Metastatic castrate-resistant prostate cancer
  • Optimal control
  • Evolutionary game theory
  • Competitive release
  • Eco-evolutionary dynamics
  • Adaptive therapy
  • ANDROGEN SUPPRESSION
  • BREAST-CANCER
  • TUMOR-GROWTH
  • CHEMOTHERAPY
  • MODEL
  • OPTIMIZATION
  • PROTOCOLS
  • SCHEDULE
  • TOXICITY
  • DYNAMICS

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