Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer

Jessica J. Cunningham*, Joel S. Brown, Robert A. Gatenby, Katerina Stankova

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)67-78
Number of pages12
JournalJournal of Theoretical Biology
Volume459
DOIs
Publication statusPublished - 14 Dec 2018

Keywords

  • Metastatic castrate-resistant prostate cancer
  • Optimal control
  • Evolutionary game theory
  • Competitive release
  • Eco-evolutionary dynamics
  • Adaptive therapy
  • ANDROGEN SUPPRESSION
  • BREAST-CANCER
  • TUMOR-GROWTH
  • CHEMOTHERAPY
  • MODEL
  • OPTIMIZATION
  • PROTOCOLS
  • SCHEDULE
  • TOXICITY
  • DYNAMICS

Cite this

@article{df16bbba31074a73a979ebfd1d4a4108,
title = "Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer",
keywords = "Metastatic castrate-resistant prostate cancer, Optimal control, Evolutionary game theory, Competitive release, Eco-evolutionary dynamics, Adaptive therapy, ANDROGEN SUPPRESSION, BREAST-CANCER, TUMOR-GROWTH, CHEMOTHERAPY, MODEL, OPTIMIZATION, PROTOCOLS, SCHEDULE, TOXICITY, DYNAMICS",
author = "Cunningham, {Jessica J.} and Brown, {Joel S.} and Gatenby, {Robert A.} and Katerina Stankova",
year = "2018",
month = "12",
day = "14",
doi = "10.1016/j.jtbi.2018.09.022",
language = "English",
volume = "459",
pages = "67--78",
journal = "Journal of Theoretical Biology",
issn = "0022-5193",
publisher = "Elsevier Science",

}

Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer. / Cunningham, Jessica J.; Brown, Joel S.; Gatenby, Robert A.; Stankova, Katerina.

In: Journal of Theoretical Biology, Vol. 459, 14.12.2018, p. 67-78.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer

AU - Cunningham, Jessica J.

AU - Brown, Joel S.

AU - Gatenby, Robert A.

AU - Stankova, Katerina

PY - 2018/12/14

Y1 - 2018/12/14

KW - Metastatic castrate-resistant prostate cancer

KW - Optimal control

KW - Evolutionary game theory

KW - Competitive release

KW - Eco-evolutionary dynamics

KW - Adaptive therapy

KW - ANDROGEN SUPPRESSION

KW - BREAST-CANCER

KW - TUMOR-GROWTH

KW - CHEMOTHERAPY

KW - MODEL

KW - OPTIMIZATION

KW - PROTOCOLS

KW - SCHEDULE

KW - TOXICITY

KW - DYNAMICS

U2 - 10.1016/j.jtbi.2018.09.022

DO - 10.1016/j.jtbi.2018.09.022

M3 - Article

VL - 459

SP - 67

EP - 78

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

SN - 0022-5193

ER -