Opportunities and challenges of current electrophysiology research: a plea to establish 'translational electrophysiology' curricula

Dennis H. Lau, Paul G. A. Volders, Peter Kohl, Frits W. Prinzen, Antonio Zaza, Stefan Kaeaeb, Ali Oto, Ulrich Schotten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Cardiac electrophysiology has evolved into an important subspecialty in cardiovascular medicine. This is in part due to the significant advances made in our understanding and treatment of heart rhythm disorders following more than a century of scientific discoveries and research. More recently, the rapid development of technology in cellular electrophysiology, molecular biology, genetics, computer modelling, and imaging have led to the exponential growth of knowledge in basic cardiac electrophysiology. The paradigm of evidence-based medicine has led to a more comprehensive decision-making process and most likely to improved outcomes in many patients. However, implementing relevant basic research knowledge in a system of evidence-based medicine appears to be challenging. Furthermore, the current economic climate and the restricted nature of research funding call for improved efficiency of translation from basic discoveries to healthcare delivery. Here, we aim to (i) appraise the broad challenges of translational research in cardiac electrophysiology, (ii) highlight the need for improved strategies in the training of translational electrophysiologists, and (iii) discuss steps towards building a favourable translational research environment and culture.
Original languageEnglish
Pages (from-to)825-833
JournalEP Europace
Issue number5
Publication statusPublished - 1 May 2015


  • Translational research
  • Electrophysiology
  • Training
  • Arrhythmia
  • Cellular electrophysiology
  • Biological models
  • Curriculum


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