Open PHACTS: semantic interoperability for drug discovery

A.J. Williams, L. Harland, P. Groth, S. Pettifer, C. Chichester, E.L. Willighagen, C.T. Evelo, N. Blomberg, G. Ecker, C. Goble, B. Mons

Research output: Contribution to journalArticleAcademicpeer-review

146 Citations (Scopus)

Abstract

Open PHACTS is a public-private partnership between academia, publishers, small and medium sized enterprises and pharmaceutical companies. The goal of the project is to deliver and sustain an 'open pharmacological space' using and enhancing state-of-the-art semantic web standards and technologies. It is focused on practical and robust applications to solve specific questions in drug discovery research. OPS is intended to facilitate improvements in drug discovery in academia and industry and to support open innovation and in-house non-public drug discovery research. This paper lays out the challenges and how the Open PHACTS project is hoping to address these challenges technically and socially.
Original languageEnglish
Pages (from-to)1188-1198
Number of pages11
JournalDrug Discovery Today
Volume17
Issue number21-22
DOIs
Publication statusPublished - Nov 2012

Keywords

  • CHEMICAL INFORMATION
  • CHEMISTRY DATABASES
  • KNOWLEDGE
  • CHEMINFORMATICS
  • INTEGRATION
  • MEDICINES
  • FRAMEWORK
  • SYSTEMS
  • WEB

Cite this

Williams, A. J., Harland, L., Groth, P., Pettifer, S., Chichester, C., Willighagen, E. L., Evelo, C. T., Blomberg, N., Ecker, G., Goble, C., & Mons, B. (2012). Open PHACTS: semantic interoperability for drug discovery. Drug Discovery Today, 17(21-22), 1188-1198. https://doi.org/10.1016/j.drudis.2012.05.016