Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination

Evelien Houben, Kris Janssens, Doryssa Hermans, Jennifer Vandooren, Chris Van den Haute, Melissa Schepers, Tim Vanmierlo, Ivo Lambrichts, Jack van Horssen, Veerle Baekelandt, Ghislain Opdenakker, Wia Baron, Bieke Broux, Helena Slaets, Niels Hellings*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)5028-5038
Number of pages11
JournalProceedings of the National Academy of Sciences of the United States of America
Volume117
Issue number9
DOIs
Publication statusPublished - 3 Mar 2020

Keywords

  • oncostatin M
  • remyelination
  • oligodendrocyte precursor cells
  • astrocytes
  • tissue inhibitor of metalloproteinases-1
  • OLIGODENDROCYTE PROGENITOR CELLS
  • CENTRAL-NERVOUS-SYSTEM
  • MULTIPLE-SCLEROSIS
  • MEDIATED DEMYELINATION
  • UP-REGULATION
  • RECEPTOR
  • EXPRESSION
  • CNS
  • PROTECTS
  • LIF

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