Omniligase-1: A Powerful Tool for Peptide Head-to-Tail Cyclization

Marcel Schmidt, Ana Toplak, Peter J. L. M. Quaedflieg, Hans Ippel, Gaston J. J. Richelle, Tilman M. Hackeng, Jan H. van Maarseveen, Timo Nuijens*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2050-2055
Number of pages6
JournalAdvanced Synthesis & Catalysis
Volume359
Issue number12
DOIs
Publication statusPublished - 19 Jun 2017

Keywords

  • chemo-enzymatic peptide synthesis (CEPS)
  • cyclic peptides
  • cyclization
  • cyclotide synthesis
  • cyclotides
  • enzyme catalysis
  • head-to-tail cyclization
  • ligases
  • macrocycles
  • omniligase-1
  • peptides
  • SQUASH TRYPSIN-INHIBITOR
  • CYSTINE KNOT PROTEINS
  • MOMORDICA-COCHINCHINENSIS
  • SEGMENT CONDENSATION
  • CIRCULAR PROTEINS
  • MCOTI-II
  • BACKBONE
  • CYCLOTIDES
  • LIGASE
  • MACROCYCLIZATION

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