Omniligase-1: A Powerful Tool for Peptide Head-to-Tail Cyclization

Marcel Schmidt, Ana Toplak, Peter J. L. M. Quaedflieg, Hans Ippel, Gaston J. J. Richelle, Tilman M. Hackeng, Jan H. van Maarseveen, Timo Nuijens*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2050-2055
Number of pages6
JournalAdvanced Synthesis & Catalysis
Volume359
Issue number12
DOIs
Publication statusPublished - 19 Jun 2017

Keywords

  • chemo-enzymatic peptide synthesis (CEPS)
  • cyclic peptides
  • cyclization
  • cyclotide synthesis
  • cyclotides
  • enzyme catalysis
  • head-to-tail cyclization
  • ligases
  • macrocycles
  • omniligase-1
  • peptides
  • SQUASH TRYPSIN-INHIBITOR
  • CYSTINE KNOT PROTEINS
  • MOMORDICA-COCHINCHINENSIS
  • SEGMENT CONDENSATION
  • CIRCULAR PROTEINS
  • MCOTI-II
  • BACKBONE
  • CYCLOTIDES
  • LIGASE
  • MACROCYCLIZATION

Cite this

Schmidt, M., Toplak, A., Quaedflieg, P. J. L. M., Ippel, H., Richelle, G. J. J., Hackeng, T. M., van Maarseveen, J. H., & Nuijens, T. (2017). Omniligase-1: A Powerful Tool for Peptide Head-to-Tail Cyclization. Advanced Synthesis & Catalysis, 359(12), 2050-2055. https://doi.org/10.1002/adsc.201700314