Omics technologies to understand drug toxicity mechanisms

Nhan Nguyen, Danyel Jennen*, Jos Kleinjans

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

Abstract

Drug side effects are an important study subject in pharmacology. Recent omics technologies provide a range of omics data and help to understand the biological mechanisms involved in drug effects. These modern technologies provide significant support to all biological disciplines, including drug toxicology. In this review, we provide an overview the use of omics applications to understand drug side effects at the molecular level. We discuss by available omics technologies, their possible uses, as well as their advantages and limitations.

Original languageEnglish
Pages (from-to)103348
Number of pages7
JournalDrug Discovery Today
Volume27
Issue number11
DOIs
Publication statusE-pub ahead of print - 8 Sept 2022

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