OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency

M. Ullrich, M. Weber, A. M. Post, S. Popp, J. Grein, M. Zechner, H. Guerrero Gonzalez, A. Kreis, A. G. Schmitt, N. Uceyler, K-P Lesch, K. Schuh

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)444-458
Number of pages15
JournalMolecular Psychiatry
Volume23
Issue number2
DOIs
Publication statusPublished - 1 Feb 2018

Keywords

  • OBSESSIVE-COMPULSIVE DISORDER
  • METABOTROPIC GLUTAMATE RECEPTORS
  • NEUROTROPHIC FACTOR
  • SYNAPTIC PLASTICITY
  • POSTSYNAPTIC DENSITY
  • ANXIETY DISORDER
  • MOUSE MODELS
  • ACTIVE ZONE
  • BDNF
  • ROLES

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