Nutritional strategies to attenuate postprandial glycemic response

Kenneth Pasmans, Ruth C R Meex, Luc J C van Loon, Ellen E Blaak*

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

Abstract

Maintaining good glycemic control to prevent complications is crucial in people with type 2 diabetes and in people with prediabetes and in the general population. Different strategies to improve glycemic control involve the prescription of blood glucose-lowering drugs and the modulation of physical activity and diet. Interestingly, lifestyle intervention may be more effective in lowering hyperglycemia than pharmaceutical intervention. Regulation of postprandial glycemia is complex, but specific nutritional strategies can be applied to attenuate postprandial hyperglycemia. These strategies include reducing total carbohydrate intake, consuming carbohydrates with a lower glycemic index, the addition of or substitution by sweeteners and fibers, using food compounds which delay or inhibit gastric emptying or carbohydrate digestion, and using food compounds which inhibit intestinal glucose absorption. Nevertheless, it must be noted that every individual may respond differently to certain nutritional interventions. Therefore, a personalized approach is of importance to choose the optimal nutritional strategy to improve postprandial glycemia for each individual, but this requires a better understanding of the mechanisms explaining the differential responses between individuals.

Original languageEnglish
Article number13486
Pages (from-to)e13486
Number of pages11
JournalObesity Reviews
Volume23
Issue number9
Early online date10 Jun 2022
DOIs
Publication statusPublished - Sept 2022

Keywords

  • ALPHA-GLUCOSIDASE INHIBITORS
  • BLOOD-GLUCOSE
  • CARBOHYDRATE MEAL
  • CO-INGESTION
  • DIABETES PREVENTION PROGRAM
  • INSULINEMIC RESPONSES
  • INULIN-TYPE FRUCTANS
  • ISOMALTULOSE INGESTION IMPLICATIONS
  • L-ARABINOSE
  • SOLUBLE DIETARY FIBER
  • alpha-glucosidase inhibitor
  • dietary fiber
  • postprandial hyperglycemia
  • type 2 diabetes

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