Nutritional depletion and dietary manipulation: effects on the immune response.

K.W.E. Hulsewé; B.A.C. van Acker; M.F. von Meyenfeldt; P.B. Soeters

doi:10.1007/PL00012344

Nutritional depletion and dietary manipulation: effects on the immune response.

K.W.E. Hulsewé^*, B.A.C. van Acker, M.F. von Meyenfeldt, P.B. Soeters

^*Corresponding author for this work

NUTRIM - Institute of Nutrition and Translational Research in Metabolism

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Department of Surgery, University Hospital Maastricht, P. Debyelaan 25, 6202AZ Maastricht, The Netherlands.

The association between nutritional depletion and the increased susceptibility for infectious diseases has been recognized for a long time. The complexity of the immune system, however, makes it difficult to unravel the underlying mechanisms. It appears that depletion adversely affects virtually all components of the immune system. This review provides an overview over the specific requirements of substrates by immune cells and the effects of nutritional depletion on various components of the immune response, with special attention to gut-associated lymphoid tissue. The literature concerning effects of dietary interventions with specific nutrients on the immune response is also discussed. Finally, we offer a hypothesis with regard to the improvement of composition of "trauma" nutrition solutions.

Publication Types:
Review
Review, Tutorial

Original language	English
Pages (from-to)	536-544
Number of pages	9
Journal	World Journal of Surgery
Volume	23
Issue number	6
DOIs	https://doi.org/10.1007/PL00012344
Publication status	Published - 1 Jan 1999

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abstract = "Department of Surgery, University Hospital Maastricht, P. Debyelaan 25, 6202AZ Maastricht, The Netherlands.The association between nutritional depletion and the increased susceptibility for infectious diseases has been recognized for a long time. The complexity of the immune system, however, makes it difficult to unravel the underlying mechanisms. It appears that depletion adversely affects virtually all components of the immune system. This review provides an overview over the specific requirements of substrates by immune cells and the effects of nutritional depletion on various components of the immune response, with special attention to gut-associated lymphoid tissue. The literature concerning effects of dietary interventions with specific nutrients on the immune response is also discussed. Finally, we offer a hypothesis with regard to the improvement of composition of {"}trauma{"} nutrition solutions.Publication Types: Review Review, Tutorial",

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AU - Hulsewé, K.W.E.

AU - van Acker, B.A.C.

AU - von Meyenfeldt, M.F.

AU - Soeters, P.B.

PY - 1999/1/1

Y1 - 1999/1/1

N2 - Department of Surgery, University Hospital Maastricht, P. Debyelaan 25, 6202AZ Maastricht, The Netherlands.The association between nutritional depletion and the increased susceptibility for infectious diseases has been recognized for a long time. The complexity of the immune system, however, makes it difficult to unravel the underlying mechanisms. It appears that depletion adversely affects virtually all components of the immune system. This review provides an overview over the specific requirements of substrates by immune cells and the effects of nutritional depletion on various components of the immune response, with special attention to gut-associated lymphoid tissue. The literature concerning effects of dietary interventions with specific nutrients on the immune response is also discussed. Finally, we offer a hypothesis with regard to the improvement of composition of "trauma" nutrition solutions.Publication Types: Review Review, Tutorial

AB - Department of Surgery, University Hospital Maastricht, P. Debyelaan 25, 6202AZ Maastricht, The Netherlands.The association between nutritional depletion and the increased susceptibility for infectious diseases has been recognized for a long time. The complexity of the immune system, however, makes it difficult to unravel the underlying mechanisms. It appears that depletion adversely affects virtually all components of the immune system. This review provides an overview over the specific requirements of substrates by immune cells and the effects of nutritional depletion on various components of the immune response, with special attention to gut-associated lymphoid tissue. The literature concerning effects of dietary interventions with specific nutrients on the immune response is also discussed. Finally, we offer a hypothesis with regard to the improvement of composition of "trauma" nutrition solutions.Publication Types: Review Review, Tutorial

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VL - 23

SP - 536

EP - 544

JO - World Journal of Surgery

JF - World Journal of Surgery

IS - 6

ER -

Nutritional depletion and dietary manipulation: effects on the immune response.

Abstract

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