Novel fungicidal benzylsulfanyl-phenylguanidines

Karin Thevissen; Klaartje Pellens; Katrijn De Brucker; Isabelle E. J. A. Francois; Kwok K. Chow; Els M. K. Meert; Wim Meert; Geert Van Minnebruggen; Marcel Borgers; Valerie Vroome; Jeremy Levin; Dirk De Vos; Louis Maes; Paul Cos; Bruno P. A. Cammue

doi:10.1016/j.bmcl.2011.04.075

Novel fungicidal benzylsulfanyl-phenylguanidines

Karin Thevissen^*
, Klaartje Pellens
, Katrijn De Brucker
, Isabelle E. J. A. Francois
, Kwok K. Chow
, Els M. K. Meert
, Wim Meert
, Geert Van Minnebruggen
, Marcel Borgers
, Valerie Vroome
, Jeremy Levin
, Dirk De Vos
, Louis Maes
, Paul Cos
, Bruno P. A. Cammue

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A series of substituted benzylsulfanyl-phenylamines was synthesized, of which four substituted benzylsulfanyl-phenylguanidines (665, 666, 667 and 684) showed potent fungicidal activity (minimal fungicidal concentration, MFC

Original language	English
Pages (from-to)	3686-3692
Number of pages	7
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	21
Issue number	12
DOIs	https://doi.org/10.1016/j.bmcl.2011.04.075
Publication status	Published - 15 Jun 2011

Keywords

Fungicidal
Benzylsulfanyl-phenylguanidines
Biofilm
Candida albicans

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10.1016/j.bmcl.2011.04.075

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Thevissen, K., Pellens, K., De Brucker, K., Francois, I. E. J. A., Chow, K. K., Meert, E. M. K., Meert, W., Van Minnebruggen, G., Borgers, M., Vroome, V., Levin, J., De Vos, D., Maes, L., Cos, P., & Cammue, B. P. A. (2011). Novel fungicidal benzylsulfanyl-phenylguanidines. Bioorganic & Medicinal Chemistry Letters, 21(12), 3686-3692. https://doi.org/10.1016/j.bmcl.2011.04.075

@article{776026e9185e4bbf8f8c4fd05b115632,

title = "Novel fungicidal benzylsulfanyl-phenylguanidines",

abstract = "A series of substituted benzylsulfanyl-phenylamines was synthesized, of which four substituted benzylsulfanyl-phenylguanidines (665, 666, 667 and 684) showed potent fungicidal activity (minimal fungicidal concentration, MFC ",

keywords = "Fungicidal, Benzylsulfanyl-phenylguanidines, Biofilm, Candida albicans",

author = "Karin Thevissen and Klaartje Pellens and \{De Brucker\}, Katrijn and Francois, \{Isabelle E. J. A.\} and Chow, \{Kwok K.\} and Meert, \{Els M. K.\} and Wim Meert and \{Van Minnebruggen\}, Geert and Marcel Borgers and Valerie Vroome and Jeremy Levin and \{De Vos\}, Dirk and Louis Maes and Paul Cos and Cammue, \{Bruno P. A.\}",

year = "2011",

month = jun,

day = "15",

doi = "10.1016/j.bmcl.2011.04.075",

language = "English",

volume = "21",

pages = "3686--3692",

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T1 - Novel fungicidal benzylsulfanyl-phenylguanidines

AU - Thevissen, Karin

AU - Pellens, Klaartje

AU - De Brucker, Katrijn

AU - Francois, Isabelle E. J. A.

AU - Chow, Kwok K.

AU - Meert, Els M. K.

AU - Meert, Wim

AU - Van Minnebruggen, Geert

AU - Borgers, Marcel

AU - Vroome, Valerie

AU - Levin, Jeremy

AU - De Vos, Dirk

AU - Maes, Louis

AU - Cos, Paul

AU - Cammue, Bruno P. A.

PY - 2011/6/15

Y1 - 2011/6/15

N2 - A series of substituted benzylsulfanyl-phenylamines was synthesized, of which four substituted benzylsulfanyl-phenylguanidines (665, 666, 667 and 684) showed potent fungicidal activity (minimal fungicidal concentration, MFC

AB - A series of substituted benzylsulfanyl-phenylamines was synthesized, of which four substituted benzylsulfanyl-phenylguanidines (665, 666, 667 and 684) showed potent fungicidal activity (minimal fungicidal concentration, MFC

KW - Fungicidal

KW - Benzylsulfanyl-phenylguanidines

KW - Biofilm

KW - Candida albicans

U2 - 10.1016/j.bmcl.2011.04.075

DO - 10.1016/j.bmcl.2011.04.075

M3 - Article

C2 - 21576022

SN - 0960-894X

VL - 21

SP - 3686

EP - 3692

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

IS - 12

ER -

Novel fungicidal benzylsulfanyl-phenylguanidines

Abstract

Keywords

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