Novel fungicidal benzylsulfanyl-phenylguanidines

Karin Thevissen; Klaartje Pellens; Katrijn De Brucker; Isabelle E. J. A. Francois; Kwok K. Chow; Els M. K. Meert; Wim Meert; Geert Van Minnebruggen; Marcel Borgers; Valerie Vroome; Jeremy Levin; Dirk De Vos; Louis Maes; Paul Cos; Bruno P. A. Cammue

doi:10.1016/j.bmcl.2011.04.075

Novel fungicidal benzylsulfanyl-phenylguanidines

Karin Thevissen^*, Klaartje Pellens, Katrijn De Brucker, Isabelle E. J. A. Francois, Kwok K. Chow, Els M. K. Meert, Wim Meert, Geert Van Minnebruggen, Marcel Borgers, Valerie Vroome, Jeremy Levin, Dirk De Vos, Louis Maes, Paul Cos, Bruno P. A. Cammue

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A series of substituted benzylsulfanyl-phenylamines was synthesized, of which four substituted benzylsulfanyl-phenylguanidines (665, 666, 667 and 684) showed potent fungicidal activity (minimal fungicidal concentration, MFC

Original language	English
Pages (from-to)	3686-3692
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	21
Issue number	12
DOIs	https://doi.org/10.1016/j.bmcl.2011.04.075
Publication status	Published - 15 Jun 2011

Keywords

Fungicidal
Benzylsulfanyl-phenylguanidines
Biofilm
Candida albicans

Access to Document

10.1016/j.bmcl.2011.04.075

Cite this

Thevissen, K., Pellens, K., De Brucker, K., Francois, I. E. J. A., Chow, K. K., Meert, E. M. K., Meert, W., Van Minnebruggen, G., Borgers, M., Vroome, V., Levin, J., De Vos, D., Maes, L., Cos, P., & Cammue, B. P. A. (2011). Novel fungicidal benzylsulfanyl-phenylguanidines. Bioorganic & Medicinal Chemistry Letters, 21(12), 3686-3692. https://doi.org/10.1016/j.bmcl.2011.04.075

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abstract = "A series of substituted benzylsulfanyl-phenylamines was synthesized, of which four substituted benzylsulfanyl-phenylguanidines (665, 666, 667 and 684) showed potent fungicidal activity (minimal fungicidal concentration, MFC ",

keywords = "Fungicidal, Benzylsulfanyl-phenylguanidines, Biofilm, Candida albicans",

author = "Karin Thevissen and Klaartje Pellens and {De Brucker}, Katrijn and Francois, {Isabelle E. J. A.} and Chow, {Kwok K.} and Meert, {Els M. K.} and Wim Meert and {Van Minnebruggen}, Geert and Marcel Borgers and Valerie Vroome and Jeremy Levin and {De Vos}, Dirk and Louis Maes and Paul Cos and Cammue, {Bruno P. A.}",

year = "2011",

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doi = "10.1016/j.bmcl.2011.04.075",

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AU - Thevissen, Karin

AU - Pellens, Klaartje

AU - De Brucker, Katrijn

AU - Francois, Isabelle E. J. A.

AU - Chow, Kwok K.

AU - Meert, Els M. K.

AU - Meert, Wim

AU - Van Minnebruggen, Geert

AU - Borgers, Marcel

AU - Vroome, Valerie

AU - Levin, Jeremy

AU - De Vos, Dirk

AU - Maes, Louis

AU - Cos, Paul

AU - Cammue, Bruno P. A.

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AB - A series of substituted benzylsulfanyl-phenylamines was synthesized, of which four substituted benzylsulfanyl-phenylguanidines (665, 666, 667 and 684) showed potent fungicidal activity (minimal fungicidal concentration, MFC

KW - Fungicidal

KW - Benzylsulfanyl-phenylguanidines

KW - Biofilm

KW - Candida albicans

U2 - 10.1016/j.bmcl.2011.04.075

DO - 10.1016/j.bmcl.2011.04.075

M3 - Article

C2 - 21576022

SN - 0960-894X

VL - 21

SP - 3686

EP - 3692

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

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