Novel bradycardia pacing strategies

L. Heckman, P. Vijayaraman, J. Luermans, A.M.W. Stipdonk, F. Salden, A.H. Maass, F.W. Prinzen, K. Vernooy*

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

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Abstract

The adverse effects of ventricular dyssynchrony induced by right ventricular (RV) pacing has led to alternative pacing strategies, such as biventricular, His bundle (HBP), LV septal (LVSP) and left bundle branch pacing (LBBP). Given the overlap, LVSP and LBBP are also collectively referred to as left bundle branch area pacing (LBBAP). Although among these alternative pacing sites HBP is theoretically the ideal strategy as it maintains a physiological ventricular activation, its application requires more skills and is associated with the most complications. LBBAP, where the ventricular pacing lead is advanced through the interventricular septum to its left side, creates ventricular activation that is only slightly more dyssynchronous. Preliminary studies have shown that LBBAP is feasible, safe and encounters less limitations than HBP. Further studies are needed to differentiate between LVSP and LBBP with regard to acute functional and long-term clinical outcome.
Original languageEnglish
Pages (from-to)1883-1889
Number of pages7
JournalHeart
Volume106
Issue number24
DOIs
Publication statusPublished - 1 Dec 2020

Keywords

  • activation
  • atrial-fibrillation
  • bradyarrhythmias
  • cardiac-resynchronization therapy
  • dual-chamber
  • heart-failure
  • his-bundle
  • implantable defibrillator
  • pacemakers
  • permanent
  • pump function
  • site
  • SITE
  • ACTIVATION
  • HEART-FAILURE
  • CARDIAC-RESYNCHRONIZATION THERAPY
  • HIS-BUNDLE
  • DUAL-CHAMBER
  • ATRIAL-FIBRILLATION
  • IMPLANTABLE DEFIBRILLATOR
  • PUMP FUNCTION
  • PERMANENT

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