Novel approach for advanced personalized cancer treatment

Anna Luise Grab; Ramesh Utharala; Thorsten Cramer; Julio Saez-Rodrigue; Nicolas Peschke; Denes Türei; Wenwei Ma; Vida Vafaizdah; Federica Eduati; Christoph Merten

Novel approach for advanced personalized cancer treatment

Anna Luise Grab^*, Ramesh Utharala, Thorsten Cramer, Julio Saez-Rodrigue, Nicolas Peschke, Denes Türei, Wenwei Ma, Vida Vafaizdah, Federica Eduati, Christoph Merten

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceeding › Academic › peer-review

Abstract

The global incidence rate of cancer cases increases with 18 Mio. (2018) new diagnosis a year. Most patients get a standard therapy, which is often not the best fit. The key problem is that each patient and each tumor responses differently to drugs. Here we address solid tumor biopsies from colon cancer patients. We present high-throughput drug-screening, which allows to determine the efficiency of individual and combinatorial drugs, including antibodies, pathway inhibitors or cytokines to recommend the best personalized therapy for the patient.

Original language	English
Title of host publication	MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	270-271
Number of pages	2
ISBN (Electronic)	9781733419017
Publication status	Published - 1 Jan 2020
Event	24th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Online, Unknown Duration: 4 Oct 2020 → 9 Oct 2020 Conference number: 24

Conference

Conference	24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Abbreviated title	MicroTAS 2020
Country/Territory	Unknown
Period	4/10/20 → 9/10/20

Keywords

Best Personalized Therapy
Cancer Cell Apoptosis
Cell Signaling
High-Throughput Drug Screening

Cite this

@inproceedings{98f5a18218234e909184b97543ebd2d2,

title = "Novel approach for advanced personalized cancer treatment",

abstract = "The global incidence rate of cancer cases increases with 18 Mio. (2018) new diagnosis a year. Most patients get a standard therapy, which is often not the best fit. The key problem is that each patient and each tumor responses differently to drugs. Here we address solid tumor biopsies from colon cancer patients. We present high-throughput drug-screening, which allows to determine the efficiency of individual and combinatorial drugs, including antibodies, pathway inhibitors or cytokines to recommend the best personalized therapy for the patient.",

keywords = "Best Personalized Therapy, Cancer Cell Apoptosis, Cell Signaling, High-Throughput Drug Screening",

author = "Grab, {Anna Luise} and Ramesh Utharala and Thorsten Cramer and Julio Saez-Rodrigue and Nicolas Peschke and Denes T{\"u}rei and Wenwei Ma and Vida Vafaizdah and Federica Eduati and Christoph Merten",

note = "Funding Information: I acknowledge the funding of our technology on both, clinical applicability and commercialization, which has been recognized by the German Ministry of Economy and Energy by EXIST grant. Publisher Copyright: {\textcopyright} 2020 CBMS-0001; 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 ; Conference date: 04-10-2020 Through 09-10-2020",

year = "2020",

month = jan,

day = "1",

language = "English",

pages = "270--271",

booktitle = "MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Chemical and Biological Microsystems Society",

address = "United States",

}

Grab, AL, Utharala, R, Cramer, T, Saez-Rodrigue, J, Peschke, N, Türei, D, Ma, W, Vafaizdah, V, Eduati, F & Merten, C 2020, Novel approach for advanced personalized cancer treatment. in MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, pp. 270-271, 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Unknown, 4/10/20.

Novel approach for advanced personalized cancer treatment. / Grab, Anna Luise; Utharala, Ramesh; Cramer, Thorsten et al.
MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2020. p. 270-271.

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceeding › Academic › peer-review

TY - GEN

T1 - Novel approach for advanced personalized cancer treatment

AU - Grab, Anna Luise

AU - Utharala, Ramesh

AU - Cramer, Thorsten

AU - Saez-Rodrigue, Julio

AU - Peschke, Nicolas

AU - Türei, Denes

AU - Ma, Wenwei

AU - Vafaizdah, Vida

AU - Eduati, Federica

AU - Merten, Christoph

N1 - Conference code: 24

PY - 2020/1/1

Y1 - 2020/1/1

N2 - The global incidence rate of cancer cases increases with 18 Mio. (2018) new diagnosis a year. Most patients get a standard therapy, which is often not the best fit. The key problem is that each patient and each tumor responses differently to drugs. Here we address solid tumor biopsies from colon cancer patients. We present high-throughput drug-screening, which allows to determine the efficiency of individual and combinatorial drugs, including antibodies, pathway inhibitors or cytokines to recommend the best personalized therapy for the patient.

AB - The global incidence rate of cancer cases increases with 18 Mio. (2018) new diagnosis a year. Most patients get a standard therapy, which is often not the best fit. The key problem is that each patient and each tumor responses differently to drugs. Here we address solid tumor biopsies from colon cancer patients. We present high-throughput drug-screening, which allows to determine the efficiency of individual and combinatorial drugs, including antibodies, pathway inhibitors or cytokines to recommend the best personalized therapy for the patient.

KW - Best Personalized Therapy

KW - Cancer Cell Apoptosis

KW - Cell Signaling

KW - High-Throughput Drug Screening

M3 - Conference article in proceeding

SP - 270

EP - 271

BT - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society

T2 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 4 October 2020 through 9 October 2020

ER -

Novel approach for advanced personalized cancer treatment

Abstract

Conference

Keywords

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Cite this