NOTCH signaling promotes the survival of irradiated basal airway stem cells

Lorena Giuranno, Carolien Wansleeben, Raffaella Iannone, Louise Arathoon, Judith Hounjet, Arjan J. Groot, Marc Vooijs*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)L414-L423
Number of pages10
JournalAmerican Journal of Physiology-Lung Cellular and Molecular Physiology
Volume317
Issue number3
DOIs
Publication statusPublished - Sep 2019

Keywords

  • basal stem cells
  • DNA damage response
  • lung organoids
  • NOTCH signaling
  • primary bronchial epithelial cells
  • radiation-induced lung injury
  • radiotherapy
  • SECRETASE INHIBITION
  • LUNG
  • RADIATION
  • REGENERATION
  • DIFFERENTIATION
  • ACTIVATION
  • CLARA
  • HOMEOSTASIS
  • MECHANISMS
  • REGULATOR

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